Alsatinib 20mg Tablet

About

Alsatinib 20mg Tablet is an oral targeted therapy, a lower-dose formulation of a potent tyrosine kinase inhibitor (TKI), utilized in the management of various oncological conditions. This medication functions by precisely inhibiting specific protein kinases that play critical roles in the growth, proliferation, and survival of cancer cells. By disrupting these aberrant signaling pathways, Alsatinib effectively controls tumor progression in cancers that are driven by these molecular targets. The 20mg dosage is often used for initial treatment, dose escalation, or in patients who require a lower dose due to tolerability issues or specific clinical indications. Its targeted mechanism allows for a more precise therapeutic effect compared to conventional chemotherapy, often leading to improved outcomes in patients with specific genetic profiles. Close monitoring for efficacy and adverse events is crucial to ensure optimal patient management and safety throughout the treatment period.

Uses

• Treatment of specific types of solid tumors.
• Management of certain hematological malignancies.
• Targeted therapy for cancers with specific genetic mutations.
• Disease control in advanced or metastatic cancer.

Directions For Use

Take orally once daily with or without food, as directed by your oncologist. Do not crush, chew, or break the tablet.

Benefits

• Targets specific cancer pathways, leading to higher efficacy.
• Oral administration offers convenience for patients.
• May improve progression-free survival in responsive cancers.
• Potentially fewer systemic side effects than traditional chemotherapy.
• Effective in cancers with specific genetic markers.
• Offers a personalized treatment approach.

Side Effects

• Fatigue.
• Nausea and vomiting.
• Diarrhea.
• Rash.
• Hand-foot syndrome.
• Hypertension (high blood pressure).
• Headache.
• Edema (swelling).
• Abdominal pain.
• Changes in liver function tests.
• Myelosuppression (low blood counts).
• QT prolongation (cardiac effect).

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may exacerbate liver-related side effects or interact with the medication's metabolism.
• Pregnancy - Contraindicated; Alsatinib can cause fetal harm. Women of childbearing potential must use effective contraception during and after treatment.
• Breastfeeding - Not recommended; it is unknown if Alsatinib is excreted in human milk and could harm a breastfed infant. Discontinue breastfeeding.
• Liver - Use with caution in patients with hepatic impairment; dose adjustments are often required, and liver function should be closely monitored.
• Kidney - Administer with caution in patients with renal impairment; dose adjustments may be necessary based on the degree of kidney dysfunction.
• Lung - Monitor for new or worsening respiratory symptoms (e.g., interstitial lung disease), especially in patients with pre-existing lung conditions.

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