Altaxel Nova 100mg Injection

About

Altaxel Nova 100mg Injection is a potent antineoplastic agent belonging to the taxane class of chemotherapy drugs. It works by interfering with the normal function of microtubules, which are essential for cell division. Specifically, it stabilizes microtubules, preventing their depolymerization, thereby arresting cells in the G2/M phase of the cell cycle and inducing apoptosis. This mechanism effectively inhibits the proliferation of rapidly dividing cancer cells.

Administered intravenously, Altaxel Nova is widely used in the treatment of various solid tumors. Its efficacy stems from its ability to disrupt the cellular machinery necessary for tumor growth and spread, making it a cornerstone in many chemotherapy regimens. Close monitoring for adverse effects and dose adjustments are crucial during treatment.

Uses

• Treatment of ovarian cancer.
• Management of breast cancer.
• Therapy for non-small cell lung cancer.
• Treatment of Kaposi's sarcoma.

Directions For Use

Administered intravenously by a healthcare professional. Dosage and infusion rate are determined by the patient's condition and body surface area.

Benefits

• Effective against a broad spectrum of solid tumors.
• Can be used as a first-line or subsequent therapy.
• Improves progression-free and overall survival in many cancers.
• Often used in combination with other chemotherapeutic agents.
• Available in a convenient injectable form for hospital use.
• Well-established efficacy profile in clinical practice.

Side Effects

• Bone marrow suppression (neutropenia, anemia, thrombocytopenia)
• Peripheral neuropathy (numbness, tingling)
• Alopecia (hair loss)
• Nausea and vomiting
• Diarrhea
• Muscle and joint pain (arthralgia, myalgia)
• Hypersensitivity reactions (rash, flushing, dyspnea)
• Fatigue and weakness
• Mucositis (inflammation of mucous membranes)
• Fluid retention (edema)
• Changes in liver function tests
• Nail changes

Safety Measures

• Alcohol - Avoid alcohol during treatment as it may exacerbate side effects like nausea or liver toxicity.
• Pregnancy - Contraindicated in pregnancy due to significant risk of fetal harm. Effective contraception is required.
• Breastfeeding - Not recommended during breastfeeding as the drug may pass into breast milk and harm the infant.
• Liver - Use with caution in patients with liver impairment; dose adjustments may be necessary due to altered metabolism.
• Kidney - Use with caution in patients with kidney impairment; dose adjustments may be necessary based on renal function.
• Lung - Monitor for pulmonary toxicity, though less common, especially in patients with pre-existing lung conditions.

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