Altraz 1mg Tablet

About

Altraz 1mg Tablet is a potent, selective, non-steroidal aromatase inhibitor primarily used in the treatment of hormone-receptor-positive breast cancer in postmenopausal women. Its mechanism of action involves blocking the enzyme aromatase, which is responsible for converting androgens into estrogens in peripheral tissues. In postmenopausal women, this peripheral conversion is the primary source of circulating estrogen. By significantly reducing estrogen levels, Altraz deprives estrogen-sensitive breast cancer cells of the growth stimulus they require, thereby inhibiting tumor growth and progression.

This targeted therapy is a crucial component of adjuvant treatment following surgery, as well as for first-line treatment of advanced disease or for patients who have progressed on tamoxifen therapy. The reduction in estrogen levels achieved by Altraz helps to decrease the risk of cancer recurrence and improve disease-free survival. Regular monitoring for bone mineral density and lipid profiles is important during treatment due to potential long-term side effects associated with estrogen deprivation.

Uses

• Adjuvant treatment of early breast cancer
• First-line treatment of advanced breast cancer
• Treatment of advanced breast cancer after tamoxifen
• Management of hormone-receptor-positive breast cancer

Directions For Use

Take one Altraz 1mg Tablet orally once daily, with or without food, preferably at the same time each day, as prescribed by your doctor.

Benefits

• Reduces risk of breast cancer recurrence
• Effective in hormone-sensitive tumors
• Oral administration for patient convenience
• Improves disease-free survival rates
• Alternative for tamoxifen-resistant cases
• Well-established efficacy in postmenopausal women

Side Effects

• Hot flashes
• Joint pain (arthralgia)
• Nausea
• Fatigue and weakness
• Headache
• Bone thinning (osteoporosis)
• Vaginal dryness
• Hair thinning
• Skin rash
• Elevated cholesterol levels
• Carpal tunnel syndrome
• Peripheral edema

Safety Measures

• Alcohol - Moderate alcohol consumption is generally acceptable, but excessive intake may exacerbate hot flashes, a common side effect of Altraz.
• Pregnancy - Altraz is contraindicated in pregnancy as it can cause fetal harm. Women of childbearing potential must use effective contraception.
• Breastfeeding - Not recommended during breastfeeding as it is unknown if Altraz is excreted in human milk and could potentially harm the infant.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be needed, and liver function should be monitored.
• Kidney - No dose adjustment is typically required in patients with renal impairment, but caution is advised in severe cases.
• Lung - Generally safe; no specific lung-related precautions are usually necessary with Altraz.

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