Armotraz 1mg Tablet

About

Armotraz 1mg Tablet contains Anastrozole, an aromatase inhibitor primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. Aromatase is an enzyme responsible for converting androgens into estrogens in peripheral tissues, which is the main source of estrogen in postmenopausal women. By selectively inhibiting this enzyme, Anastrozole significantly reduces circulating estrogen levels, thereby depriving estrogen-sensitive breast cancer cells of the growth stimulus they require. This action helps to slow or stop the growth of hormone-dependent tumors.

This medication is typically prescribed as adjuvant therapy after surgery, or for the treatment of advanced breast cancer. It is taken orally, usually once daily. Regular monitoring for bone mineral density and lipid profiles is important during treatment, as aromatase inhibitors can affect these parameters. The goal of therapy is to prevent recurrence, reduce tumor size, and improve overall survival in eligible patients by effectively lowering estrogen levels.

Uses

• Adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women.
• First-line treatment of hormone receptor-positive advanced breast cancer in postmenopausal women.
• Treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.
• Reduces the risk of recurrence in high-risk patients.

Directions For Use

Take one tablet orally once daily, with or without food, as directed by your oncologist. Do not miss doses.

Benefits

• Significantly reduces estrogen levels in postmenopausal women.
• Effective in preventing breast cancer recurrence.
• Slows the progression of advanced hormone-sensitive breast cancer.
• Offers a well-tolerated oral treatment option.
• Improves disease-free survival in eligible patients.
• Can be used as a first-line or second-line therapy.

Side Effects

• Hot flashes
• Joint pain (arthralgia)
• Nausea
• Fatigue
• Headache
• Bone thinning (osteoporosis)
• Vaginal dryness
• Hair thinning
• Weight gain
• High cholesterol
• Rash
• Carpal tunnel syndrome

Safety Measures

• Alcohol - Moderate alcohol consumption is generally acceptable, but excessive intake should be avoided as it may exacerbate hot flashes or liver strain.
• Pregnancy - Armotraz is contraindicated in premenopausal women and during pregnancy due to potential fetal harm. Not applicable for postmenopausal women.
• Breastfeeding - Not applicable as Armotraz is for postmenopausal women. If a woman were to become pregnant and breastfeed, it would be contraindicated.
• Liver - Use with caution in patients with moderate to severe liver impairment. Dose adjustments may be considered, and liver function should be monitored.
• Kidney - No dose adjustment is generally required for mild to moderate renal impairment. Use with caution in severe renal impairment.
• Lung - Generally safe for patients with lung conditions. No specific pulmonary concerns are typically associated with anastrozole.

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