Anastronat 1mg Tablet

About

Anastronat 1mg Tablet contains anastrozole, a potent and selective non-steroidal aromatase inhibitor. Aromatase is an enzyme that catalyzes the conversion of anandrogens to estrogens in peripheral tissues, a key source of estrogen in postmenopausal women. By inhibiting aromatase, anastrozole significantly reduces circulating estrogen levels, thereby depriving estrogen-receptor-positive breast cancer cells of the growth stimulus they require. This makes it an effective treatment for hormone-sensitive breast cancer in postmenopausal women. It is typically used as adjuvant therapy after surgery or as first-line treatment for advanced breast cancer.

Uses

• Adjuvant treatment of early breast cancer in postmenopausal women.
• First-line treatment of hormone-receptor-positive advanced breast cancer.
• Treatment of advanced breast cancer after tamoxifen therapy.
• Used in postmenopausal women with estrogen-receptor-positive tumors.

Directions For Use

Take one tablet orally once daily, with or without food.
Follow your doctor's instructions regarding the duration of treatment.

Benefits

• Effective in reducing estrogen levels.
• Reduces risk of breast cancer recurrence.
• Improves disease-free survival.
• Well-tolerated for long-term use.
• Oral administration for convenience.
• Specific for hormone-receptor-positive cancers.

Side Effects

• Hot flashes
• Joint pain (arthralgia)
• Headache
• Nausea
• Fatigue
• Bone thinning (osteoporosis)
• Vaginal dryness
• Hair thinning
• Rash
• High blood pressure
• Peripheral edema
• Carpal tunnel syndrome

Safety Measures

• Alcohol - Moderate alcohol consumption is generally acceptable, but excessive intake may worsen hot flashes or liver effects.
• Pregnancy - Anastrozole is contraindicated in pregnant women due to potential harm to the fetus.
• Breastfeeding - It is not known if anastrozole is excreted in human milk. Breastfeeding is not recommended during treatment.
• Liver - Use with caution in patients with moderate to severe hepatic impairment; monitor liver function.
• Kidney - No dose adjustment is generally required for patients with mild to moderate renal impairment.
• Lung - No specific precautions are typically needed for patients with pre-existing lung conditions.

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