About
Atorvastatin and Fenofibrate combination therapy is a potent pharmacological strategy employed for the comprehensive management of mixed dyslipidemia, particularly in patients presenting with elevated triglycerides, low high-density lipoprotein cholesterol (HDL-C), and high low-density lipoprotein cholesterol (LDL-C), where single-agent therapy has proven inadequate. Atorvastatin, a highly effective HMG-CoA reductase inhibitor, works by blocking the enzyme crucial for cholesterol synthesis in the liver, leading to a significant reduction in LDL-C and total cholesterol. Fenofibrate, a fibric acid derivative, primarily targets triglyceride reduction and HDL-C elevation through its action as a peroxisome proliferator-activated receptor alpha (PPAR_) agonist. This synergistic combination offers a robust approach to lipid modification, addressing multiple facets of dyslipidemia and substantially mitigating the risk of atherosclerotic cardiovascular events in high-risk populations.
Uses
Mixed dyslipidemia.
Hypertriglyceridemia with low HDL-C.
Primary hypercholesterolemia.
Prevention of cardiovascular events in high-risk patients.
Directions For Use
Take orally once daily with or without food, as directed by your healthcare provider.
Benefits
Significantly lowers LDL-C and total cholesterol.
Effectively reduces elevated triglyceride levels.
Increases beneficial HDL-C levels.
Provides comprehensive lipid profile improvement.
Reduces the risk of atherosclerotic cardiovascular disease.
Offers a synergistic approach to complex dyslipidemia.
Side Effects
Muscle pain (myalgia)
Liver enzyme elevation
Gastrointestinal upset (nausea, diarrhea)
Headache
Dizziness
Pancreatitis
Gallstones
Rash
Fatigue
Insomnia
Arthralgia (joint pain)
Peripheral edema
Safety Measures
Alcohol - Avoid excessive alcohol intake due to increased risk of liver damage and myopathy.
Pregnancy - Contraindicated in pregnancy; potential for fetal harm.
Breastfeeding - Not recommended during breastfeeding; consult a doctor.
Liver - Contraindicated in active liver disease or unexplained persistent transaminase elevations.
Kidney - Use with caution and dose adjustment in moderate to severe renal impairment.
Lung - Generally safe for lung conditions, but monitor for any unexplained respiratory symptoms.
Disclaimer
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| Shop Location | Assam, India |

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