Avastin 100mg Injection

About

Avastin 100mg Injection contains Bevacizumab, a recombinant humanized monoclonal antibody that specifically targets and neutralizes vascular endothelial growth factor (VEGF). VEGF is a protein that plays a critical role in angiogenesis, the process by which new blood vessels form to supply tumors with nutrients and oxygen. By inhibiting VEGF, Avastin prevents the formation of these new blood vessels, effectively starving the tumor and inhibiting its growth and spread.

This medication is used in combination with chemotherapy for the treatment of various advanced cancers, including metastatic colorectal cancer, non-small cell lung cancer, glioblastoma, metastatic renal cell carcinoma, and epithelial ovarian cancer, significantly improving progression-free survival.

Uses

• Metastatic colorectal cancer
• Non-small cell lung cancer
• Glioblastoma
• Metastatic renal cell carcinoma
• Epithelial ovarian cancer

Directions For Use

Administered intravenously by a healthcare professional, typically every 2-3 weeks, as part of a chemotherapy regimen.

Benefits

• Improves progression-free survival
• Enhances chemotherapy efficacy
• Reduces tumor size and growth
• Broad spectrum of cancer indications
• Well-established anti-angiogenic agent
• Can be used as maintenance therapy

Side Effects

• Hypertension
• Proteinuria
• Hemorrhage
• Arterial thromboembolic events
• Venous thromboembolic events
• Gastrointestinal perforation
• Wound healing complications
• Fatigue
• Headache
• Epistaxis
• Diarrhea
• Neutropenia
• Infusion reactions

Safety Measures

• Alcohol - No specific interaction, but general health advice to limit alcohol intake during cancer treatment.
• Pregnancy - Contraindicated during pregnancy due to potential fetal harm. Use effective contraception.
• Breastfeeding - Not recommended during breastfeeding due to the potential for serious adverse reactions in infants.
• Liver - Use with caution; monitor liver function, though it is not primarily metabolized by the liver.
• Kidney - Use with caution; monitor for proteinuria and renal function.
• Lung - Monitor for signs of pulmonary hemorrhage or other respiratory complications, especially in lung cancer patients.

Disclaimer

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