AXCER 90 BOTTLE 180S

About

Ticagrelor is an antiplatelet medication belonging to the class of P2Y12 platelet inhibitors. It works by reversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets and subsequently inhibiting platelet aggregation. This action reduces the risk of thrombotic events in patients with acute coronary syndromes (ACS) or a history of myocardial infarction. Its rapid onset and offset of action, compared to some other antiplatelets, make it a crucial component in dual antiplatelet therapy (DAPT) alongside aspirin to prevent further cardiovascular events.

It is typically used in high-risk patients to improve cardiovascular outcomes by reducing the incidence of stent thrombosis, stroke, and cardiovascular death. Ticagrelor is a direct-acting agent that does not require metabolic activation, providing consistent antiplatelet effects. It is an essential therapy for secondary prevention in patients with established atherosclerotic disease.

Uses

• Prevention of atherothrombotic events in patients with acute coronary syndrome (ACS).
• Reduction of cardiovascular death, myocardial infarction, and stroke in patients with a history of MI.
• Prevention of stent thrombosis after percutaneous coronary intervention (PCI).
• Used in combination with aspirin for dual antiplatelet therapy.

Directions For Use

Take exactly as prescribed by your doctor, usually twice daily. Do not crush or break the tablets.

Benefits

• Significantly reduces the risk of heart attack and stroke.
• Lowers the chance of cardiovascular death in high-risk patients.
• Effective in preventing stent thrombosis after PCI.
• Rapid onset of antiplatelet action.
• Reversible platelet inhibition.
• Improves long-term cardiovascular outcomes.

Side Effects

• Bleeding (e.g., nosebleeds, bruising)
• Dyspnea (shortness of breath)
• Headache
• Nausea
• Diarrhea
• Dizziness
• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)
• Rash
• Gout
• Increased uric acid levels
• Abnormal liver function tests

Safety Measures

• Alcohol - Alcohol can increase the risk of bleeding when taken with ticagrelor. It is advisable to limit or avoid alcohol consumption.
• Pregnancy - Ticagrelor is generally not recommended during pregnancy unless the potential benefit outweighs the risk to the fetus. Consult your doctor.
• Breastfeeding - It is unknown if ticagrelor is excreted in human milk. A decision should be made whether to discontinue nursing or the drug, considering the importance of the drug to the mother.
• Liver - Use with caution in patients with moderate hepatic impairment; it is contraindicated in severe hepatic impairment due to increased exposure and bleeding risk.
• Kidney - No dose adjustment is typically required for patients with renal impairment, but caution is advised in severe cases.
• Lung - Ticagrelor can cause dyspnea; use with caution in patients with pre-existing respiratory conditions like asthma or COPD.

Disclaimer

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