TGROLIS 90 10'S

About

TGROLIS 90 is a medication primarily used for the management of dyslipidemia, specifically to lower elevated levels of total cholesterol, LDL-cholesterol, and triglycerides, and to increase HDL-cholesterol. It typically belongs to the class of HMG-CoA reductase inhibitors, commonly known as statins. Statins work by inhibiting the enzyme HMG-CoA reductase, which is a key enzyme in the liver responsible for cholesterol synthesis. By reducing cholesterol production, the liver increases its uptake of LDL-cholesterol from the bloodstream, thereby lowering circulating LDL levels.

This action is crucial in preventing the progression of atherosclerosis and reducing the risk of major cardiovascular events such as heart attack and stroke. TGROLIS 90 is an important component of a comprehensive cardiovascular risk reduction strategy, alongside diet and lifestyle modifications.

Uses

• Reduction of elevated total cholesterol and LDL-cholesterol.
• Treatment of hypertriglyceridemia.
• Prevention of cardiovascular events in high-risk patients.
• Management of primary dysbetalipoproteinemia.

Directions For Use

Take one tablet orally once daily, preferably in the evening, with or without food, as directed by your physician.

Benefits

• Significantly lowers LDL-cholesterol.
• Reduces risk of heart attack and stroke.
• Slows progression of atherosclerosis.
• Improves overall lipid profile.
• Well-established efficacy and safety.
• Can be used for primary and secondary prevention.

Side Effects

• Myalgia (muscle pain)
• Headache
• Nausea
• Diarrhea
• Abdominal pain
• Fatigue
• Insomnia
• Elevated liver enzymes
• Arthralgia
• Rash
• Memory impairment (rare)
• Rhabdomyolysis (very rare, severe muscle breakdown)

Safety Measures

• Alcohol - Excessive alcohol consumption may increase the risk of liver damage, a potential side effect of statins. It is advisable to limit alcohol intake while on this medication.
• Pregnancy - Statins are contraindicated during pregnancy due to the potential for fetal harm. Cholesterol is essential for fetal development.
• Breastfeeding - Statins are contraindicated during breastfeeding as they may be excreted in breast milk and could potentially harm the infant.
• Liver - Contraindicated in patients with active liver disease or unexplained persistent elevations of serum transaminases. Liver function tests should be monitored regularly.
• Kidney - Use with caution in patients with severe renal impairment, as dose adjustments may be necessary for some statins.
• Lung - Generally safe for use in patients with lung conditions. No specific pulmonary adverse effects are commonly associated with statins.

Disclaimer

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