Azatirel 100mg

About

Azathioprine is an immunosuppressive agent widely utilized in the prevention of organ transplant rejection and the management of severe autoimmune diseases. It functions as a purine analog, interfering with DNA and RNA synthesis, which in turn inhibits the proliferation of rapidly dividing cells, particularly lymphocytes. Lymphocytes are crucial components of the immune system responsible for mediating immune responses. By suppressing their activity, azathioprine effectively dampens the overall immune response, reducing inflammation and preventing the body from attacking transplanted organs or its own tissues in autoimmune conditions such as rheumatoid arthritis, Crohn's disease, and ulcerative colitis. Due to its mechanism, careful monitoring of blood counts and liver function is essential during treatment.

Uses

• Prevention of organ transplant rejection
• Rheumatoid arthritis
• Crohn's disease
• Ulcerative colitis

Directions For Use

Take orally once daily or as prescribed by your doctor, usually with food to reduce stomach upset.

Benefits

• Prevents organ transplant rejection
• Manages autoimmune diseases
• Reduces inflammation
• Suppresses immune response
• Available in oral form
• Long-term disease control

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Loss of appetite
• Bone marrow suppression (leukopenia, thrombocytopenia)
• Increased risk of infection
• Hepatotoxicity
• Pancreatitis
• Rash
• Hair loss
• Mouth sores
• Increased risk of certain cancers (long-term use)

Safety Measures

• Alcohol - Avoid or limit alcohol due to increased risk of liver damage.
• Pregnancy - Generally not recommended; discuss risks with your doctor as it may cause fetal harm.
• Breastfeeding - Avoid breastfeeding as the drug can pass into breast milk and affect the infant.
• Liver - Contraindicated in severe liver disease; monitor liver function closely.
• Kidney - Use with caution in renal impairment; dose adjustment may be necessary.
• Lung - Rarely associated with interstitial pneumonitis; monitor for new respiratory symptoms.

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