Azishil 100mg Injection

About

Azishil 100mg Injection, likely containing Azithromycin, is a macrolide antibiotic used to treat a wide range of bacterial infections. It works by inhibiting bacterial protein synthesis, specifically by binding to the 50S ribosomal subunit of susceptible microorganisms. This action prevents bacteria from growing and multiplying, thereby clearing the infection.

Azithromycin is known for its broad-spectrum activity against various Gram-positive and Gram-negative bacteria, as well as atypical pathogens. Its unique pharmacokinetic properties, including a long tissue half-life, allow for once-daily dosing and shorter treatment courses, making it a convenient and effective option for many patients requiring intravenous antibiotic therapy.

Uses

• Treatment of community-acquired pneumonia
• Management of pelvic inflammatory disease
• Therapy for skin and soft tissue infections
• Treatment of pharyngitis/tonsillitis caused by susceptible bacteria

Directions For Use

Administered intravenously, typically once daily. Follow prescribed dosage and infusion rate strictly as directed by a healthcare professional.

Benefits

• Broad-spectrum antibacterial activity
• Convenient once-daily dosing regimen
• Good penetration into various body tissues
• Effective against atypical bacterial pathogens
• Suitable for patients with penicillin allergies
• Generally well-tolerated with a favorable safety profile

Side Effects

• Nausea
• Diarrhea
• Abdominal pain
• Vomiting
• Headache
• Dizziness
• Rash
• QT prolongation (cardiac rhythm changes)
• Liver enzyme elevation
• Injection site reactions (pain, swelling)
• Fungal infections (oral or vaginal)
• Palpitations

Safety Measures

• Alcohol - Moderate alcohol consumption is generally not contraindicated, but excessive intake may exacerbate gastrointestinal side effects.
• Pregnancy - Generally considered safe for use during pregnancy when clearly needed, but use only if potential benefits outweigh risks. Consult a doctor.
• Breastfeeding - Excreted into breast milk in small amounts. Use with caution; monitor infant for gastrointestinal disturbances like diarrhea or vomiting.
• Liver - Use with caution in patients with hepatic impairment; monitor liver function tests. Severe liver disease may require dose adjustment or alternative therapy.
• Kidney - No dosage adjustment is typically required for mild to moderate renal impairment. Use with caution in severe renal impairment.
• Lung - Generally safe for lung conditions, but monitor for worsening symptoms if underlying cardiac issues are present due to QT prolongation risk.

Disclaimer

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