Bdpazo 400mg Tablet

About

Bdpazo 400mg Tablet is an oral multi-targeted receptor tyrosine kinase inhibitor (TKI) used in oncology. It works by inhibiting several key tyrosine kinases involved in tumor growth, angiogenesis (formation of new blood vessels that feed tumors), and tumor progression. Specifically, it targets vascular endothelial growth factor receptors (VEGFR-1, -2, and -3), platelet-derived growth factor receptors (PDGFR-alpha and -beta), and c-Kit. By blocking these pathways, Bdpazo effectively disrupts the signaling cascades that promote cancer cell proliferation, survival, and metastasis, thereby slowing or halting tumor development.

This targeted therapy approach makes Bdpazo 400mg Tablet a valuable treatment option for certain advanced cancers. Its mechanism of action focuses on inhibiting the critical processes that tumors rely on for growth and spread, offering a more specific intervention compared to traditional chemotherapy. The consistent oral administration allows for sustained therapeutic levels, contributing to its efficacy in managing advanced malignancies.

Uses

• Treatment of advanced renal cell carcinoma (RCC).
• Management of advanced soft tissue sarcoma (STS).
• Treatment of other solid tumors where indicated.
• Inhibition of tumor angiogenesis.

Directions For Use

Take one tablet orally once daily, at least one hour before or two hours after a meal, as directed by your oncologist. Swallow whole.

Benefits

• Inhibits tumor growth and progression.
• Reduces angiogenesis in tumors.
• Effective in advanced renal cell carcinoma.
• Effective in advanced soft tissue sarcoma.
• Oral administration for convenience.
• Targets multiple pathways involved in cancer.

Side Effects

• Diarrhea
• Nausea
• Vomiting
• Fatigue
• Hypertension (high blood pressure)
• Hair color changes (depigmentation)
• Liver enzyme elevation
• Anorexia
• Headache
• Proteinuria
• Thrombocytopenia
• Hand-foot syndrome

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can increase the risk of liver toxicity, which is a significant concern with this medication.
• Pregnancy - Contraindicated during pregnancy due to the risk of fetal harm; effective contraception must be used during treatment and for a period after.
• Breastfeeding - Not recommended during breastfeeding as it is unknown if it is excreted into breast milk and could cause serious adverse effects in the infant.
• Liver - Use with extreme caution in patients with liver impairment; regular and frequent monitoring of liver function tests is crucial due to risk of severe hepatotoxicity.
• Kidney - Use with caution in patients with severe kidney impairment; dose adjustment may be necessary, and close monitoring is advised.
• Lung - Use with caution in patients with pre-existing lung conditions; monitor for signs of interstitial lung disease or pneumonitis, which are rare but serious side effects.

Disclaimer

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