CILAHART 20 TAB 10S

About

CILAHART 20 TAB contains Cilnidipine, a dihydropyridine calcium channel blocker (CCB) that uniquely targets both L-type and N-type voltage-dependent calcium channels. Its primary action involves inhibiting the influx of calcium ions into vascular smooth muscle cells, which results in vasodilation and a subsequent reduction in peripheral vascular resistance, thereby lowering blood pressure. The additional blockade of N-type calcium channels helps to modulate sympathetic nervous system activity, which can contribute to its overall antihypertensive effect and potentially reduce reflex tachycardia.

This dual mechanism of action makes Cilnidipine an effective agent for the management of essential hypertension, particularly when a higher dose is required for adequate blood pressure control. It is typically administered once daily, providing sustained blood pressure control throughout the day. Patients using Cilnidipine should be monitored for common CCB-related side effects, though its specific pharmacological profile may offer advantages in certain patient populations.

Uses

• Treatment of essential hypertension.
• Management of high blood pressure.
• Reduction of peripheral vascular resistance.
• Prevention of cardiovascular complications.

Directions For Use

Take orally once daily, preferably after a meal, or as advised by your doctor. Swallow the tablet whole with water.

Benefits

• Effective in lowering blood pressure.
• Dual L-type and N-type calcium channel blockade.
• May reduce sympathetic overactivity.
• Less likely to cause reflex tachycardia.
• Provides sustained antihypertensive effect.
• Generally well-tolerated for long-term use.

Side Effects

• Headache
• Dizziness
• Flushing
• Palpitations
• Edema (especially ankle edema)
• Nausea
• Fatigue
• Gingival hyperplasia (rare)
• Hypotension
• Rash
• Abdominal discomfort
• Increased heart rate (less common than other CCBs)

Safety Measures

• Alcohol - Alcohol may potentiate the hypotensive effects of Cilnidipine, leading to increased dizziness or lightheadedness. Avoid excessive alcohol consumption.
• Pregnancy - Cilnidipine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult a doctor.
• Breastfeeding - It is unknown whether Cilnidipine is excreted in human milk. Exercise caution and consult a healthcare professional before use during breastfeeding.
• Liver - Use with caution in patients with hepatic impairment, as dosage adjustments may be necessary.
• Kidney - Generally safe for use in patients with mild to moderate renal impairment; however, caution is advised in severe cases.
• Lung - Cilnidipine is generally safe for use in patients with lung conditions, as it does not directly affect respiratory function.

Disclaimer

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