About
CTD O 12.5/40 TAB is a combination medication containing Chlorthalidone (12.5mg) and Olmesartan (40mg). Chlorthalidone is a thiazide-like diuretic that acts by increasing the excretion of sodium and water, thereby reducing blood volume and peripheral vascular resistance. Olmesartan is an Angiotensin Receptor Blocker (ARB) that selectively blocks the AT1 receptor, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This dual mechanism provides a powerful and complementary approach to blood pressure control, making it highly effective for patients with essential hypertension who require more aggressive management than monotherapy can provide. The combination helps to achieve target blood pressure levels, reduce the risk of cardiovascular events, and protect vital organs from hypertension-related damage. Its once-daily administration supports patient adherence and simplifies the treatment regimen.
Uses
- Management of essential hypertension
- Reduction of cardiovascular morbidity and mortality
- Treatment of fluid overload in specific conditions
- Adjunctive therapy in heart failure management
Directions For Use
Take one tablet orally once daily, preferably at the same time each day, with or without food.
Benefits
- Provides significant and sustained blood pressure reduction
- Offers comprehensive cardiovascular protection
- Convenient once-daily dosing improves adherence
- Synergistic action of two antihypertensive agents
- Helps prevent hypertension-related organ damage
- Well-tolerated in many patient populations
Side Effects
- Dizziness or lightheadedness
- Fatigue or weakness
- Headache
- Cough (less common than ACE inhibitors)
- Low blood pressure (hypotension)
- Electrolyte imbalances (e.g., hypokalemia, hyponatremia)
- Kidney dysfunction or increased creatinine
- Muscle cramps or pain
- Nausea or diarrhea
- Increased uric acid levels (hyperuricemia)
- Hyperglycemia
- Back pain
Safety Measures
- Alcohol - Alcohol can potentiate hypotensive effects and increase the risk of dizziness. Use with caution.
- Pregnancy - Contraindicated during the second and third trimesters due to severe risk of fetal injury and death.
- Breastfeeding - Not recommended during breastfeeding as components may be excreted in breast milk. Consult a healthcare provider.
- Liver - Use with caution in patients with hepatic impairment; dose adjustment may be required.
- Kidney - Contraindicated in severe renal impairment; close monitoring of renal function is crucial.
- Lung - Generally safe, but monitor for electrolyte disturbances that could indirectly affect respiratory status.
Disclaimer
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| Shop Location | Assam, India |
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