OLKEM TRIO 6.25 TAB

About Olkem Trio 6.25 is a triple combination medication containing Olmesartan, Amlodipine, and Hydrochlorothiazide, designed for the comprehensive management of essential hypertension. Olmesartan is an angiotensin II receptor blocker (ARB) that blocks vasoconstriction and aldosterone secretion. Amlodipine is a dihydropyridine calcium channel blocker (CCB) that causes peripheral vasodilation. Hydrochlorothiazide is a thiazide diuretic that increases the excretion of sodium and water. This synergistic combination targets multiple pathways involved in blood pressure regulation, providing potent and sustained antihypertensive effects, particularly in patients whose blood pressure is not adequately controlled with dual therapy. It helps to reduce the overall risk of cardiovascular morbidity and mortality associated with uncontrolled hypertension. Uses Treatment of essential hypertension. When blood pressure is not adequately controlled with dual therapy. Reduction of cardiovascular risk in hypertensive patients. Management of fluid retention associated with hypertension. Directions For Use Take this medication orally, usually once daily, with or without food, as directed by your doctor. Swallow the tablet whole with water. Benefits Potent and sustained blood pressure reduction. Multiple mechanisms of action for comprehensive control. Improved adherence with a single-pill combination. Reduces risk of cardiovascular events. Effective for resistant hypertension. Helps manage fluid balance and peripheral edema. Side Effects Dizziness Headache Peripheral edema (swelling of ankles/feet) Fatigue Nausea Diarrhea Muscle cramps Hypotension Electrolyte imbalance (e.g., hypokalemia) Increased urination Flushing Palpitations Safety Measures Alcohol - Avoid excessive alcohol consumption as it may increase the risk of low blood pressure, dizziness, and exacerbate side effects. Pregnancy - Contraindicated during pregnancy, especially in the second and third trimesters, due to potential fetal harm and death. Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk and harm the infant. Consult a doctor. Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be necessary, and HCTZ may precipitate hepatic coma. Kidney - Use with caution in patients with renal artery stenosis or severe renal impairment; monitor kidney function and electrolytes closely. Lung - Generally safe for use in patients with lung conditions; however, HCTZ should be used with caution in patients with a history of allergy or asthma. Disclaimer MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment. Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub. Our goal is to complement, not replace, the essential doctor-patient relationship.