OLMIN TRIO 20 10S

About

OLMIN TRIO 20 is a fixed-dose combination medication designed to provide comprehensive blood pressure control, likely containing Olmesartan (an angiotensin II receptor blocker), Amlodipine (a dihydropyridine calcium channel blocker), and Hydrochlorothiazide (a thiazide diuretic). Olmesartan blocks the effects of angiotensin II, leading to vasodilation and reduced aldosterone. Amlodipine relaxes vascular smooth muscle, causing peripheral vasodilation. Hydrochlorothiazide increases the excretion of sodium and water, reducing blood volume. This triple combination targets multiple pathways involved in blood pressure regulation, offering synergistic effects to achieve significant and sustained reductions in hypertension, particularly in patients whose blood pressure is not adequately controlled by monotherapy or dual therapy.

Uses

• Treatment of essential hypertension.
• Management of severe or resistant hypertension.
• Achieving target blood pressure in complex cases.
• Reducing cardiovascular risk associated with high BP.

Directions For Use

Take this medication orally, usually once daily, with or without food, as directed by your physician.

Benefits

• Provides powerful and sustained blood pressure reduction.
• Combines three distinct mechanisms of action.
• Effective for resistant hypertension.
• Reduces the risk of cardiovascular events.
• Offers convenient once-daily dosing.
• Improves patient adherence to therapy.

Side Effects

• Dizziness
• Headache
• Peripheral edema (swelling)
• Fatigue
• Nausea
• Diarrhea
• Cough (less common than ACE inhibitors)
• Hypotension (low blood pressure)
• Hyperkalemia (due to ARB)
• Hypokalemia (due to diuretic)
• Increased urination
• Muscle cramps

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it can further lower blood pressure and increase the risk of dizziness or lightheadedness.
• Pregnancy - Olmesartan is contraindicated during the second and third trimesters of pregnancy due to potential fetal harm.
• Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk and potentially harm the infant.
• Liver - Use with caution in patients with hepatic impairment; dose adjustment may be necessary.
• Kidney - Contraindicated in anuria and severe renal impairment. Monitor kidney function and electrolytes closely.
• Lung - Generally safe for use in patients with lung conditions, but monitor for any unusual respiratory symptoms.

Disclaimer

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