About
This medication is a combination therapy indicated for the management of essential hypertension, particularly in patients whose blood pressure is not adequately controlled with Olmesartan monotherapy. It combines Olmesartan 40mg, an angiotensin II receptor blocker (ARB), with Hydrochlorothiazide, a thiazide diuretic. Olmesartan works by selectively blocking the binding of angiotensin II to the AT1 receptor, leading to vasodilation and reduced aldosterone secretion, which helps lower blood pressure. Hydrochlorothiazide increases the excretion of sodium and chloride by inhibiting their reabsorption in the distal convoluted tubule, thereby reducing plasma volume and blood pressure. The synergistic action of these two agents provides enhanced blood pressure control through complementary mechanisms, making it an effective option for achieving target blood pressure and reducing cardiovascular risk.
Uses
- Treatment of essential hypertension.
- When Olmesartan monotherapy is insufficient.
- Reduction of cardiovascular risk in hypertensive patients.
- Management of fluid retention associated with hypertension.
Directions For Use
Take orally once daily, preferably at the same time each day, with or without food, as directed by your physician.
Benefits
- Effective blood pressure reduction.
- Dual mechanism of action.
- Improved patient adherence.
- Helps manage fluid balance.
- Reduces risk of cardiovascular events.
- Suitable for moderate hypertension.
Side Effects
- Dizziness
- Headache
- Fatigue
- Nausea
- Hypotension
- Electrolyte imbalance (e.g., hypokalemia)
- Muscle cramps
- Increased urination
- Cough
- Rash
- Diarrhea
- Upper respiratory tract infection
Safety Measures
- Alcohol - Avoid or limit alcohol consumption as it can further lower blood pressure and increase the risk of dizziness.
- Pregnancy - Contraindicated during pregnancy, especially in the second and third trimesters, due to potential fetal harm.
- Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk and affect the infant.
- Liver - Use with caution in patients with hepatic impairment; dosage adjustments may be necessary.
- Kidney - Use with caution in patients with renal impairment; monitor kidney function closely.
- Lung - Generally safe for use in patients with lung conditions, but monitor for any unusual respiratory symptoms.
Disclaimer
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| Shop Location | Assam, India |
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