About
TELVAS 3D 10 is a sophisticated combination medication primarily prescribed for the management of essential hypertension, particularly in patients whose blood pressure is not adequately controlled by monotherapy or dual therapy. This formulation typically combines an angiotensin II receptor blocker (ARB), a calcium channel blocker (CCB), and a thiazide diuretic, each working through distinct mechanisms to achieve comprehensive blood pressure reduction. The ARB component, such as telmisartan, blocks the action of angiotensin II, leading to vasodilation and reduced aldosterone secretion.
The CCB, like amlodipine, relaxes vascular smooth muscle, further lowering peripheral vascular resistance. The diuretic component, such as hydrochlorothiazide, promotes the excretion of sodium and water, thereby reducing blood volume and cardiac preload. This synergistic action helps to achieve optimal blood pressure control, reducing the risk of cardiovascular events such as stroke and myocardial infarction. The triple combination offers a robust approach for patients requiring aggressive blood pressure management.
Uses
- Management of essential hypertension.
- Blood pressure control in patients unresponsive to dual therapy.
- Reduction of cardiovascular risk in hypertensive patients.
- Treatment of high blood pressure with fluid retention.
Directions For Use
Take one tablet orally once daily, preferably at the same time each day, with or without food, as directed by your physician.
Benefits
- Comprehensive blood pressure control.
- Reduced risk of cardiovascular events.
- Improved patient adherence due to single pill.
- Effective for resistant hypertension.
- Synergistic action of multiple drug classes.
- Helps manage fluid retention.
Side Effects
- Dizziness
- Headache
- Fatigue
- Peripheral edema
- Nausea
- Diarrhea
- Hypotension
- Hyperkalemia (less common with diuretic)
- Hypokalemia (due to diuretic)
- Cough (less common than ACEIs)
- Muscle cramps
- Increased urination
Safety Measures
- Alcohol - Concurrent use of alcohol may enhance the hypotensive effect and increase the risk of dizziness or lightheadedness. It is advisable to limit or avoid alcohol consumption.
- Pregnancy - This medication is contraindicated in the second and third trimesters of pregnancy due to potential fetal harm (renal dysfunction, oligohydramnios, fetal death). Use in the first trimester is generally not recommended.
- Breastfeeding - Components of this medication may be excreted into breast milk. Due to potential adverse effects on the infant, breastfeeding is generally not recommended while taking this drug.
- Liver - Use with caution in patients with hepatic impairment, as dose adjustments may be necessary. Close monitoring of liver function is advised.
- Kidney - Use with caution in patients with renal impairment. Regular monitoring of kidney function and electrolytes is crucial, and dose adjustments may be required.
- Lung - Generally safe for use in patients with lung conditions, but caution is advised if the patient has severe electrolyte imbalances or fluid overload that could impact respiratory function.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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