TELPRESS CT 40/6.25

AboutTelpress CT 40/6.25 is a fixed-dose combination medication indicated for the effective treatment of essential hypertension, especially in patients who require more than monotherapy to achieve their target blood pressure. This formulation combines telmisartan, an angiotensin receptor blocker (ARB) at a dose of 40mg, with hydrochlorothiazide, a thiazide diuretic at 6.25mg. Telmisartan exerts its antihypertensive effect by selectively blocking the angiotensin II type 1 (AT1) receptor, preventing vasoconstriction and aldosterone secretion. Hydrochlorothiazide complements this action by increasing the excretion of sodium and water through the kidneys, leading to a reduction in plasma volume and peripheral resistance. The synergistic action of these two agents provides a robust and sustained reduction in blood pressure, thereby mitigating the long-term risks of cardiovascular disease, including stroke and myocardial infarction. This combination offers a convenient once-daily dosing regimen, enhancing patient adherence and overall therapeutic outcomes.UsesTreatment of essential hypertensionBlood pressure control when monotherapy is insufficientReduction of cardiovascular riskManagement of fluid retentionDirections For UseTake one tablet orally once daily, with or without food. Swallow the tablet whole with water.BenefitsEffective blood pressure reductionReduces risk of heart attack and strokeConvenient once-daily dosingSynergistic antihypertensive effectHelps manage fluid balanceImproved patient complianceSide EffectsDizzinessHeadacheFatigueNauseaDiarrheaHypotensionHypokalemiaHyperuricemiaMuscle crampsIncreased urinationCough (less common than ACE inhibitors)Skin rashSafety MeasuresAlcohol - Avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase dizziness.Pregnancy - Contraindicated, especially in the second and third trimesters, due to potential fetal harm or death.Breastfeeding - Not recommended. Components may pass into breast milk and could harm the infant.Liver - Use with caution in patients with severe hepatic impairment. Dosage adjustments may be necessary.Kidney - Use with caution in patients with severe renal impairment. Monitor kidney function closely; contraindicated in anuria.Lung - Generally safe for lung conditions. No specific contraindications related to lung function.DisclaimerMedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.Our goal is to complement, not replace, the essential doctor-patient relationship.