TELPRESS CT 40/6.25 10'S

About

Telpress CT 40/6.25 is a fixed-dose combination medication indicated for the effective treatment of essential hypertension, especially in patients who require more than monotherapy to achieve their target blood pressure. This formulation combines telmisartan, an angiotensin receptor blocker (ARB) at a dose of 40mg, with hydrochlorothiazide, a thiazide diuretic at 6.25mg. Telmisartan exerts its antihypertensive effect by selectively blocking the angiotensin II type 1 (AT1) receptor, preventing vasoconstriction and aldosterone secretion. Hydrochlorothiazide complements this action by increasing the excretion of sodium and water through the kidneys, leading to a reduction in plasma volume and peripheral resistance. The synergistic action of these two agents provides a robust and sustained reduction in blood pressure, thereby mitigating the long-term risks of cardiovascular disease, including stroke and myocardial infarction. This combination offers a convenient once-daily dosing regimen, enhancing patient adherence and overall therapeutic outcomes.

Uses

• Treatment of essential hypertension
• Blood pressure control when monotherapy is insufficient
• Reduction of cardiovascular risk
• Management of fluid retention

Directions For Use

Take one tablet orally once daily, with or without food. Swallow the tablet whole with water.

Benefits

• Effective blood pressure reduction
• Reduces risk of heart attack and stroke
• Convenient once-daily dosing
• Synergistic antihypertensive effect
• Helps manage fluid balance
• Improved patient compliance

Side Effects

• Dizziness
• Headache
• Fatigue
• Nausea
• Diarrhea
• Hypotension
• Hypokalemia
• Hyperuricemia
• Muscle cramps
• Increased urination
• Cough (less common than ACE inhibitors)
• Skin rash

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase dizziness.
• Pregnancy - Contraindicated, especially in the second and third trimesters, due to potential fetal harm or death.
• Breastfeeding - Not recommended. Components may pass into breast milk and could harm the infant.
• Liver - Use with caution in patients with severe hepatic impairment. Dosage adjustments may be necessary.
• Kidney - Use with caution in patients with severe renal impairment. Monitor kidney function closely; contraindicated in anuria.
• Lung - Generally safe for lung conditions. No specific contraindications related to lung function.

Disclaimer

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