About
Telmisartan is an angiotensin receptor blocker (ARB) that works by selectively blocking the binding of angiotensin II to its receptors, leading to the relaxation of blood vessels and a subsequent reduction in blood pressure. Amlodipine, a dihydropyridine calcium channel blocker, acts by inhibiting the influx of calcium ions into vascular smooth muscle and myocardial cells, causing peripheral vasodilation and lowering blood pressure. This combination medication is specifically indicated for the treatment of essential hypertension, providing a powerful dual mechanism of action to effectively lower and maintain blood pressure within a healthy range. It is particularly beneficial for patients whose blood pressure is not adequately controlled by monotherapy with either telmisartan or amlodipine alone. The synergistic effect of these two agents offers comprehensive cardiovascular protection, reducing the risk of serious cardiovascular events such as stroke, myocardial infarction, and heart failure, thereby improving long-term patient outcomes and quality of life.
Uses
- Treatment of essential hypertension.
- Management of high blood pressure in adults.
- Prevention of cardiovascular events in high-risk patients.
- When monotherapy with either telmisartan or amlodipine is inadequate.
Directions For Use
Take this medication orally, usually once daily, with or without food, as directed by your physician.
Benefits
- Effective blood pressure reduction.
- Dual mechanism of action for comprehensive control.
- Reduces risk of stroke and heart attack.
- Improved patient compliance with combination therapy.
- Provides sustained blood pressure control.
- Suitable for patients requiring more aggressive BP management.
Side Effects
- Dizziness
- Headache
- Fatigue
- Swelling in ankles/feet (edema)
- Flushing
- Nausea
- Abdominal pain
- Palpitations
- Cough
- Diarrhea
- Muscle cramps
- Hypotension
Safety Measures
- Alcohol - Avoid excessive alcohol consumption as it can further lower blood pressure and increase the risk of dizziness.
- Pregnancy - Contraindicated during the second and third trimesters due to potential fetal harm; consult a doctor if pregnant or planning pregnancy.
- Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk and affect the infant.
- Liver - Use with caution in patients with severe liver impairment; dose adjustment may be necessary.
- Kidney - Use with caution in patients with renal artery stenosis or severe kidney impairment; monitor kidney function closely.
- Lung - Generally safe for use in patients with lung conditions; no specific contraindications related to pulmonary function.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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