AMLOSAFE TM 80 10

About

AMLOSAFE TM 80 combines Amlodipine, a dihydropyridine calcium channel blocker, with Telmisartan, an angiotensin II receptor blocker (ARB). This combination therapy is highly effective in treating essential hypertension by targeting two distinct mechanisms. Amlodipine causes peripheral vasodilation by relaxing vascular smooth muscle, while Telmisartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Together, they provide comprehensive and sustained blood pressure reduction, helping to prevent cardiovascular events such as stroke and myocardial infarction, especially in patients whose blood pressure is not adequately controlled by monotherapy. This dual action ensures a more robust and consistent control of hypertension.

Uses

• Treatment of essential hypertension.
• Management of high blood pressure not controlled by single agents.
• Reduction of cardiovascular risk in hypertensive patients.
• Prevention of target organ damage associated with hypertension.

Directions For Use

Take one tablet orally once daily, with or without food, as directed by your physician.

Benefits

• Potent and sustained blood pressure control.
• Targets multiple pathways for hypertension management.
• Reduces the risk of heart attack and stroke.
• Provides 24-hour blood pressure lowering.
• Improved patient compliance with a single pill.
• Offers superior efficacy compared to monotherapy for many patients.

Side Effects

• Dizziness
• Headache
• Peripheral edema (swelling of ankles/feet)
• Fatigue
• Nausea
• Flushing
• Palpitations
• Hypotension
• Hyperkalemia
• Cough (less common than ACE inhibitors)
• Abdominal pain
• Muscle cramps

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it may increase hypotensive effects and risk of dizziness.
• Pregnancy - Contraindicated during the second and third trimesters due to fetal harm risk; avoid in the first trimester.
• Breastfeeding - Not recommended during breastfeeding as both components may pass into breast milk.
• Liver - Use with caution in patients with hepatic impairment; dosage adjustment may be necessary.
• Kidney - Use with caution in patients with renal impairment; monitor kidney function regularly.
• Lung - Generally safe for use in patients with lung conditions; no specific contraindications related to pulmonary function.

Disclaimer

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