CTD T 12.5/40 TAB 10.S

About

CTD T 12.5/40 TAB is a combination medication comprising Chlorthalidone (12.5mg) and Telmisartan (40mg). Chlorthalidone is a thiazide-like diuretic that works by increasing the excretion of sodium and water from the body, thereby reducing blood volume and blood pressure. Telmisartan is an Angiotensin Receptor Blocker (ARB) that selectively blocks the binding of angiotensin II to its AT1 receptor, leading to vasodilation and a reduction in aldosterone secretion, which further lowers blood pressure. This synergistic action makes the combination highly effective in managing essential hypertension. It is often prescribed when monotherapy is insufficient to achieve target blood pressure levels, offering comprehensive cardiovascular protection by addressing multiple pathways involved in blood pressure regulation. The sustained action of both components allows for convenient once-daily dosing, improving patient adherence and long-term outcomes in hypertension management.

Uses

• Management of essential hypertension
• Reduction of cardiovascular risk in high-risk patients
• Adjunctive therapy in certain forms of edema
• Prevention of stroke and myocardial infarction

Directions For Use

Take one tablet orally once daily, with or without food, as directed by your physician.

Benefits

• Provides effective and sustained blood pressure control
• Reduces the overall risk of cardiovascular events
• Offers convenient once-daily dosing for better adherence
• Combines two distinct mechanisms for synergistic action
• Helps protect target organs from hypertension-related damage
• May improve patient outcomes compared to monotherapy

Side Effects

• Dizziness or lightheadedness
• Fatigue or weakness
• Headache
• Cough (less common than ACE inhibitors)
• Low blood pressure (hypotension)
• Electrolyte imbalances (e.g., hypokalemia, hyponatremia)
• Kidney dysfunction or increased creatinine
• Muscle cramps or pain
• Nausea or diarrhea
• Increased uric acid levels (hyperuricemia)
• Hyperglycemia
• Back pain

Safety Measures

• Alcohol - Alcohol may increase the hypotensive effects and risk of dizziness. Avoid excessive consumption.
• Pregnancy - Contraindicated during the second and third trimesters due to potential fetal harm and toxicity.
• Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk. Consult a doctor.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be necessary.
• Kidney - Contraindicated in severe renal impairment; close monitoring of kidney function is essential.
• Lung - Generally safe for lung conditions, but monitor for electrolyte imbalances that could indirectly affect respiratory function.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.