About
Telsartan 40mg contains Telmisartan, an angiotensin II receptor blocker (ARB) primarily used for the management of essential hypertension. It exerts its antihypertensive effect by selectively blocking the AT1 receptor, thereby preventing the vasoconstrictive and aldosterone-secreting actions of angiotensin II. This leads to relaxation of blood vessels, a decrease in peripheral vascular resistance, and a subsequent reduction in blood pressure. Its long half-life supports once-daily administration, contributing to patient adherence.
In addition to its role in blood pressure control, Telmisartan has been shown to reduce the risk of cardiovascular events in high-risk adult patients, including those with established atherosclerotic cardiovascular disease or type 2 diabetes with target organ damage. It is a valuable therapeutic option for patients who require effective blood pressure management and cardiovascular protection, particularly those who cannot tolerate ACE inhibitors due to side effects like persistent cough.
Uses
- Treatment of essential hypertension.
- Reduction of cardiovascular morbidity and mortality.
- Prevention of stroke and myocardial infarction in high-risk patients.
- Management of diabetic nephropathy (off-label, but common for ARBs).
Directions For Use
Take one tablet orally once daily, with or without food, as directed by your physician.
Benefits
- Effective and sustained blood pressure reduction.
- Reduces risk of stroke and heart attack.
- Once-daily dosing for convenience.
- Well-tolerated in many patients.
- Alternative for ACE inhibitor intolerant patients.
- Provides cardiovascular protection.
Side Effects
- Dizziness
- Lightheadedness
- Fatigue
- Headache
- Nausea
- Diarrhea
- Back pain
- Upper respiratory tract infection
- Hypotension
- Hyperkalemia
- Angioedema (rare)
- Renal dysfunction
Safety Measures
- Alcohol - Alcohol may increase the hypotensive effect and risk of dizziness. Use with caution.
- Pregnancy - Contraindicated in the second and third trimesters due to risk of fetal harm (renal dysfunction, oligohydramnios, fetal death).
- Breastfeeding - Not recommended during breastfeeding due to potential adverse effects on the infant. Consult a doctor.
- Liver - Use with caution in patients with severe hepatic impairment; dosage adjustment may be necessary.
- Kidney - Use with caution in patients with renal artery stenosis or severe renal impairment; monitor kidney function closely.
- Lung - Generally safe for use in patients with lung conditions, as it does not typically cause respiratory side effects like ACE inhibitors.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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