TELPRESS TRIO 12.5 10'S

About

Telpress Trio 12.5 is a sophisticated triple-combination medication specifically engineered for the comprehensive management of essential hypertension, particularly in patients whose blood pressure remains inadequately controlled despite dual-therapy regimens. This potent formulation integrates an angiotensin receptor blocker (telmisartan), a calcium channel blocker (amlodipine), and a thiazide diuretic (hydrochlorothiazide). Telmisartan works by blocking the vasoconstrictive effects of angiotensin II, amlodipine relaxes vascular smooth muscle to reduce peripheral resistance, and hydrochlorothiazide promotes the excretion of sodium and water, thereby reducing blood volume. This synergistic, multi-modal approach targets distinct physiological mechanisms involved in blood pressure regulation, leading to a more profound and sustained reduction in blood pressure. Consequently, it significantly lowers the risk of major cardiovascular events such as stroke, myocardial infarction, and heart failure, offering a robust solution for complex hypertensive cases.

Uses

• Treatment of essential hypertension
• Blood pressure control in resistant hypertension
• Prevention of cardiovascular events
• Management of fluid retention associated with hypertension

Directions For Use

Take one tablet orally once daily, preferably at the same time each day, with or without food.

Benefits

• Comprehensive blood pressure control
• Reduces risk of heart attack and stroke
• Effective for resistant hypertension
• Convenient once-daily dosing
• Targets multiple pathways of hypertension
• Improved patient adherence

Side Effects

• Dizziness
• Headache
• Fatigue
• Peripheral edema
• Nausea
• Diarrhea
• Hypotension
• Hyperkalemia (less common with diuretic)
• Hypokalemia (due to diuretic)
• Cough (less common than ACE inhibitors)
• Muscle cramps
• Increased urination

Safety Measures

• Alcohol - Avoid or limit alcohol as it can further lower blood pressure and increase the risk of dizziness or fainting.
• Pregnancy - Contraindicated, especially in the second and third trimesters, due to risk of fetal harm or death.
• Breastfeeding - Not recommended. Components may pass into breast milk and could harm the infant.
• Liver - Use with caution in patients with severe hepatic impairment. Dosage adjustments may be necessary.
• Kidney - Use with caution in patients with severe renal impairment. Monitor kidney function closely; contraindicated in anuria.
• Lung - Generally safe for lung conditions. No specific contraindications related to lung function.

Disclaimer

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