VITEL AM 40 10'S

About

VITEL AM 40 10'S is a combination medication containing Valsartan and Amlodipine, prescribed for the treatment of essential hypertension. Valsartan is an angiotensin II receptor blocker (ARB) that works by blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II, leading to vasodilation and reduced blood pressure. Amlodipine is a dihydropyridine calcium channel blocker (CCB) that relaxes vascular smooth muscle, further contributing to vasodilation and blood pressure reduction. The combination of these two agents provides complementary mechanisms of action, resulting in a more potent antihypertensive effect than either drug alone.

This dual therapy is particularly beneficial for patients whose blood pressure is not adequately controlled by monotherapy, offering comprehensive and sustained blood pressure control and reducing the risk of associated cardiovascular complications.

Uses

• Treatment of essential hypertension.
• Blood pressure control in patients unresponsive to monotherapy.
• Reduction of cardiovascular risk in hypertensive patients.
• Management of high blood pressure with associated angina (due to amlodipine).

Directions For Use

Take one tablet orally once daily, preferably at the same time each day, with or without food, as directed by your physician.

Benefits

• Potent and sustained blood pressure reduction.
• Complementary mechanisms of action.
• Reduced risk of cardiovascular events.
• Improved patient adherence with single pill.
• Effective for resistant hypertension.
• Provides angina relief (due to amlodipine).

Side Effects

• Dizziness
• Headache
• Peripheral edema
• Fatigue
• Nausea
• Hypotension
• Palpitations
• Flushing
• Cough (less common than ACEIs)
• Hyperkalemia (due to valsartan)
• Muscle cramps
• Abdominal pain

Safety Measures

• Alcohol - Concurrent use of alcohol may enhance the hypotensive effect and increase the risk of dizziness or lightheadedness. It is advisable to limit or avoid alcohol consumption.
• Pregnancy - This medication is contraindicated in the second and third trimesters of pregnancy due to potential fetal harm (renal dysfunction, oligohydramnios, fetal death). Use in the first trimester is generally not recommended.
• Breastfeeding - Both valsartan and amlodipine are excreted in breast milk. Due to potential adverse effects on the infant, breastfeeding is generally not recommended while taking this drug.
• Liver - Use with caution in patients with hepatic impairment, as dose adjustments may be necessary. Close monitoring of liver function is advised.
• Kidney - Use with caution in patients with renal impairment. Regular monitoring of kidney function and electrolytes is crucial, and dose adjustments may be required.
• Lung - Generally safe for use in patients with lung conditions, as it does not directly affect respiratory function.

Disclaimer

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