About
Stamlo Trio combines three active ingredients: Telmisartan (an angiotensin II receptor blocker), Amlodipine (a dihydropyridine calcium channel blocker), and Hydrochlorothiazide (a thiazide diuretic). Telmisartan blocks the action of angiotensin II, causing blood vessels to relax. Amlodipine further relaxes blood vessels by blocking calcium channels. Hydrochlorothiazide reduces blood volume by increasing the excretion of sodium and water. This triple combination provides a powerful and comprehensive approach to managing severe or resistant hypertension.
This multi-modal therapy targets different pathways involved in blood pressure regulation, offering superior blood pressure control compared to monotherapy or dual therapy. It is indicated for patients whose blood pressure is not adequately controlled by two-drug combinations, significantly reducing the risk of major cardiovascular events such as stroke, heart attack, and kidney disease, thereby improving long-term cardiovascular outcomes.
Uses
- Treatment of severe or resistant essential hypertension.
- Management of high blood pressure when dual therapy is insufficient.
- Reduction of cardiovascular risk in high-risk hypertensive patients.
- Prevention of stroke and heart attack in individuals with uncontrolled hypertension.
Directions For Use
Take one tablet orally once daily, with or without food, as directed by your healthcare provider.
Benefits
- Potent and comprehensive blood pressure reduction.
- Triple mechanism of action for enhanced control.
- Significantly reduces risk of major cardiovascular events.
- Once-daily dosing for patient convenience.
- Effective for resistant hypertension.
- Provides extensive cardiovascular protection.
Side Effects
- Dizziness
- Lightheadedness
- Fatigue
- Headache
- Nausea
- Peripheral edema (swelling of ankles/feet)
- Flushing
- Palpitations
- Electrolyte imbalance (e.g., hypokalemia)
- Increased uric acid levels
- Hypotension
- Upper respiratory tract infection
Safety Measures
- Alcohol - Alcohol may significantly increase the hypotensive effect and risk of dizziness. Use with extreme caution and avoid excessive consumption.
- Pregnancy - Contraindicated in the second and third trimesters due to risk of severe fetal harm (renal dysfunction, oligohydramnios, fetal death).
- Breastfeeding - Not recommended during breastfeeding as all components may pass into breast milk and potentially harm the infant.
- Liver - Use with extreme caution in patients with severe hepatic impairment; dosage adjustment is necessary, and there's an increased risk of hepatic coma with the diuretic component.
- Kidney - Use with extreme caution in patients with severe renal impairment or renal artery stenosis; monitor kidney function closely. The diuretic component is less effective in severe renal dysfunction.
- Lung - Generally safe for use in patients with lung conditions, as it does not typically cause respiratory side effects.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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| Shop Location | Assam, India |

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