About
Telsarten CT is a fixed-dose combination medication containing telmisartan, an angiotensin II receptor blocker (ARB), and chlorthalidone, a thiazide-like diuretic. This combination is prescribed for the treatment of essential hypertension, particularly when monotherapy with either agent is insufficient to achieve target blood pressure goals. Telmisartan effectively lowers blood pressure by blocking the vasoconstrictive and aldosterone-secreting effects of angiotensin II, while chlorthalidone provides sustained diuretic and antihypertensive effects by inhibiting sodium reabsorption in the renal tubules, leading to increased excretion of sodium and water.
Chlorthalidone is known for its long duration of action, which complements telmisartan's 24-hour blood pressure control, offering robust and consistent antihypertensive efficacy. The combined action helps to reduce overall cardiovascular risk by effectively managing high blood pressure. This combination therapy simplifies the dosing regimen, potentially improving patient adherence and leading to better long-term cardiovascular outcomes compared to single-agent therapy.
Uses
- Treatment of essential hypertension.
- For patients whose blood pressure is not adequately controlled by monotherapy.
- Reduction of cardiovascular morbidity and mortality.
- Provides sustained 24-hour blood pressure control.
Directions For Use
Take orally once daily, with or without food, as directed by your physician.
Benefits
- Powerful and sustained blood pressure reduction.
- Combines two complementary antihypertensive agents.
- Offers 24-hour blood pressure control due to long-acting components.
- Simplifies medication regimen, enhancing adherence.
- Reduces the risk of major cardiovascular events.
- Effective for resistant hypertension cases.
Side Effects
- Dizziness
- Headache
- Fatigue
- Nausea
- Diarrhea
- Muscle cramps
- Hypotension (low blood pressure)
- Electrolyte imbalances (e.g., hypokalemia, hyponatremia)
- Increased uric acid levels (gout risk)
- Hyperglycemia (elevated blood sugar)
- Photosensitivity
- Pancreatitis (rare)
Safety Measures
- Alcohol - Avoid excessive alcohol consumption as it can enhance the blood pressure-lowering effect and increase dizziness.
- Pregnancy - Contraindicated in the second and third trimesters due to fetal toxicity; avoid during the first trimester if possible.
- Breastfeeding - Not recommended as both components may pass into breast milk and potentially harm the infant.
- Liver - Use with caution in severe hepatic impairment; dose adjustment may be necessary, and electrolyte imbalance can precipitate hepatic encephalopathy.
- Kidney - Contraindicated in anuria and severe renal impairment; monitor kidney function and electrolytes closely.
- Lung - Generally safe, but chlorthalidone can rarely cause acute transient myopia and acute angle-closure glaucoma.
Disclaimer
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