SARTEL AM TAB 15 S

About

Telmisartan is an angiotensin II receptor blocker (ARB) that works by blocking the action of angiotensin II, a potent vasoconstrictor, leading to relaxation of blood vessels and a decrease in blood pressure. Amlodipine is a dihydropyridine calcium channel blocker (CCB) that inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, resulting in peripheral vasodilation and reduced peripheral vascular resistance.

The combination of telmisartan and amlodipine provides a comprehensive approach to managing hypertension, leveraging two distinct mechanisms to achieve effective blood pressure control. This fixed-dose combination is particularly beneficial for patients who require more aggressive blood pressure lowering or who have not achieved target blood pressure with monotherapy. It helps to reduce the risk of cardiovascular events such as stroke and myocardial infarction.

Uses

• Treatment of essential hypertension.
• Management of high blood pressure when monotherapy is inadequate.
• Reduction of cardiovascular risk in hypertensive patients.
• Prevention of angina pectoris in patients with hypertension.

Directions For Use

Take one tablet orally once daily, with or without food, as prescribed by your doctor.

Benefits

• Potent and sustained blood pressure control.
• Reduced risk of cardiovascular morbidity and mortality.
• Improved patient adherence due to once-daily dosing.
• Dual mechanism of action for comprehensive control.
• Effective for patients with resistant hypertension.
• Helps prevent angina attacks in susceptible individuals.

Side Effects

• Dizziness or lightheadedness.
• Peripheral edema (swelling of ankles/feet).
• Headache.
• Fatigue.
• Flushing.
• Nausea.
• Palpitations.
• Abdominal pain.
• Gingival hyperplasia (gum overgrowth).
• Orthostatic hypotension.
• Muscle cramps.
• Upper respiratory tract infection.

Safety Measures

• Alcohol - Limit alcohol intake as it can exacerbate blood pressure lowering and increase dizziness.
• Pregnancy - Contraindicated in the second and third trimesters; consult a doctor immediately if pregnant.
• Breastfeeding - Not recommended; components may pass into breast milk and affect the infant.
• Liver - Use with caution in patients with impaired liver function; dosage adjustment may be required.
• Kidney - Generally safe, but monitor kidney function, especially in severe impairment.
• Lung - Generally considered safe for patients with pre-existing lung conditions.

Disclaimer

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