About
This medication is a sophisticated combination of two potent antihypertensive agents: Telmisartan, an angiotensin II receptor blocker (ARB), and Amlodipine, a dihydropyridine calcium channel blocker. Telmisartan exerts its effect by selectively blocking the action of angiotensin II, a powerful vasoconstrictor, leading to the relaxation of blood vessels and a subsequent reduction in blood pressure. Concurrently, Amlodipine works by relaxing the smooth muscles in the walls of blood vessels, which further facilitates easier blood flow and lowers peripheral resistance. The synergistic action of these two components provides comprehensive and effective blood pressure control, significantly reducing the risk of severe cardiovascular events such as strokes, heart attacks, and kidney damage. It is typically prescribed for patients whose hypertension is not adequately managed by a single antihypertensive agent, offering a robust solution for achieving target blood pressure levels and improving long-term cardiovascular outcomes.
Uses
- Treatment of essential hypertension (high blood pressure).
- Management of blood pressure in patients requiring combination therapy.
- Reduction of cardiovascular risk in hypertensive patients.
- Prevention of complications associated with uncontrolled high blood pressure.
Directions For Use
Take one tablet orally once daily, preferably at the same time each day, with or without food, as directed by your physician.
Benefits
- Effective blood pressure reduction.
- Reduced risk of stroke and heart attack.
- Improved cardiovascular outcomes.
- Convenient once-daily dosing.
- Synergistic action of two different mechanisms.
- Better blood pressure control compared to monotherapy.
Side Effects
- Dizziness or lightheadedness
- Headache
- Swelling in ankles or feet (edema)
- Fatigue
- Nausea
- Abdominal pain
- Flushing
- Palpitations
- Muscle cramps
- Cough (less common than with ACE inhibitors)
- Hypotension (low blood pressure)
- Increased potassium levels
Safety Measures
- Alcohol - Alcohol can further lower blood pressure and increase the risk of dizziness or lightheadedness. It is advisable to limit or avoid alcohol consumption while on this medication.
- Pregnancy - This medication is contraindicated in the second and third trimesters of pregnancy due to potential harm to the developing fetus. Consult your doctor if you are pregnant or planning to conceive.
- Breastfeeding - It is generally not recommended during breastfeeding as components may pass into breast milk. Consult your doctor to weigh the benefits and risks.
- Liver - Use with caution in patients with liver impairment, as dosage adjustments may be necessary. Close monitoring of liver function is advised.
- Kidney - Use with caution in patients with kidney impairment. Regular monitoring of kidney function and electrolyte levels is recommended.
- Lung - Generally safe for use in patients with lung conditions, but always inform your doctor about all existing medical conditions.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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