About
Telsartan 80 contains Telmisartan, an angiotensin II receptor blocker (ARB) used primarily for the treatment of essential hypertension. It works by selectively blocking the binding of angiotensin II to the AT1 receptor in various tissues, including vascular smooth muscle. This blockade prevents the vasoconstrictive and aldosterone-secreting effects of angiotensin II, leading to vasodilation, reduced peripheral vascular resistance, and a subsequent decrease in blood pressure. Telmisartan is known for its long duration of action, allowing for once-daily dosing.
Beyond its antihypertensive effects, Telmisartan has demonstrated benefits in reducing cardiovascular morbidity and mortality in patients at high risk, such as those with a history of cardiovascular disease or diabetes with end-organ damage. It is often a preferred choice for patients who develop a cough with ACE inhibitors, offering a similar therapeutic profile without the common side effect of cough.
Uses
- Treatment of essential hypertension.
- Reduction of cardiovascular morbidity and mortality.
- Prevention of stroke and myocardial infarction in high-risk patients.
- Management of diabetic nephropathy (off-label, but common for ARBs).
Directions For Use
Take one tablet orally once daily, with or without food, as directed by your physician.
Benefits
- Effective and sustained blood pressure reduction.
- Reduces risk of stroke and heart attack.
- Once-daily dosing for convenience.
- Well-tolerated in many patients.
- Alternative for ACE inhibitor intolerant patients.
- Provides cardiovascular protection.
Side Effects
- Dizziness
- Lightheadedness
- Fatigue
- Headache
- Nausea
- Diarrhea
- Back pain
- Upper respiratory tract infection
- Hypotension
- Hyperkalemia
- Angioedema (rare)
- Renal dysfunction
Safety Measures
- Alcohol - Alcohol may increase the hypotensive effect and risk of dizziness. Use with caution.
- Pregnancy - Contraindicated in the second and third trimesters due to risk of fetal harm (renal dysfunction, oligohydramnios, fetal death).
- Breastfeeding - Not recommended during breastfeeding due to potential adverse effects on the infant. Consult a doctor.
- Liver - Use with caution in patients with severe hepatic impairment; dosage adjustment may be necessary.
- Kidney - Use with caution in patients with renal artery stenosis or severe renal impairment; monitor kidney function closely.
- Lung - Generally safe for use in patients with lung conditions, as it does not typically cause respiratory side effects like ACE inhibitors.
Disclaimer
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