CTD 12.5 TAB 15 S

About

CTD 12.5 TAB contains Chlorthalidone 12.5mg, a thiazide-like diuretic widely used in the management of hypertension and edema. Chlorthalidone works by inhibiting sodium reabsorption in the cortical diluting segment of the nephron, leading to increased excretion of sodium, chloride, and water. This diuretic action reduces extracellular fluid volume, plasma volume, and cardiac output, ultimately lowering blood pressure. Its long duration of action allows for once-daily dosing, making it a convenient and effective option for long-term blood pressure control. Beyond its diuretic effects, Chlorthalidone has demonstrated significant benefits in reducing cardiovascular morbidity and mortality in hypertensive patients, establishing its role as a cornerstone in antihypertensive therapy. It is often a first-line agent or used in combination with other antihypertensives to achieve optimal blood pressure targets.

Uses

• Treatment of essential hypertension
• Management of edema associated with heart failure
• Edema due to nephrotic syndrome
• Adjunctive therapy in mild to moderate renal dysfunction

Directions For Use

Take one tablet orally once daily, usually in the morning, with or without food, as prescribed.

Benefits

• Provides effective and sustained diuretic action
• Achieves significant blood pressure reduction
• Helps reduce fluid retention and swelling
• Cost-effective and widely available antihypertensive
• Demonstrated cardiovascular protective benefits
• Convenient once-daily dosing regimen

Side Effects

• Dizziness or lightheadedness
• Headache
• Nausea or vomiting
• Diarrhea
• Muscle cramps or weakness
• Electrolyte imbalance (e.g., hypokalemia, hyponatremia)
• Hyperglycemia (elevated blood sugar)
• Hyperuricemia (elevated uric acid, risk of gout)
• Photosensitivity or rash
• Fatigue
• Orthostatic hypotension
• Pancreatitis (rare)

Safety Measures

• Alcohol - Alcohol may increase the risk of orthostatic hypotension and dizziness. Use with caution.
• Pregnancy - Generally not recommended unless essential; consult a doctor due to potential fetal effects.
• Breastfeeding - Excreted in breast milk; not recommended during breastfeeding.
• Liver - Use with caution in severe hepatic impairment; may precipitate hepatic coma.
• Kidney - Use with caution in severe renal impairment; may be less effective and require monitoring.
• Lung - Generally safe, but monitor for electrolyte disturbances that could impact respiratory function.

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