DAJIO GM2 TAB

About

DAJIO GM2 TAB is a triple combination therapy for type 2 diabetes mellitus, likely containing Dapagliflozin, Glimepiride 2mg, and Metformin. Dapagliflozin, an SGLT2 inhibitor, increases urinary glucose excretion. Glimepiride, a sulfonylurea, stimulates insulin release from pancreatic beta cells. Metformin, a biguanide, reduces hepatic glucose production and improves insulin sensitivity. This comprehensive approach targets multiple pathways involved in glucose dysregulation, aiming for robust glycemic control. The combination provides potent HbA1c reduction, with additional benefits like weight management and cardiovascular/renal protection from Dapagliflozin. It is typically prescribed when dual therapy is insufficient to achieve adequate glycemic control, serving as an adjunct to diet and exercise.

Uses

• Management of type 2 diabetes mellitus
• Comprehensive glycemic control
• When dual therapy is insufficient
• Adjunct to diet and exercise

Directions For Use

Take orally with meals, usually once or twice daily, as directed by your physician.

Benefits

• Potent reduction in HbA1c levels
• Multi-faceted glucose control
• Potential for weight loss (Dapagliflozin)
• Cardiovascular and renal benefits (Dapagliflozin)
• Improved insulin sensitivity
• Reduced risk of diabetes-related complications

Side Effects

• Hypoglycemia (due to Glimepiride)
• Urinary tract infections
• Genital yeast infections
• Increased urination
• Nausea
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Lactic acidosis (Metformin, rare)
• Ketoacidosis (rare)
• Weight gain (Glimepiride)

Safety Measures

• Alcohol - Avoid excessive alcohol due to increased risk of lactic acidosis (Metformin) and hypoglycemia (Glimepiride).
• Pregnancy - Not recommended during pregnancy; consult your doctor. Potential for adverse effects on fetal kidney development and hypoglycemia risk.
• Breastfeeding - Not recommended during breastfeeding; consult your doctor. Metformin and Glimepiride pass into breast milk.
• Liver - Use with caution; Metformin is contraindicated in severe hepatic impairment. Glimepiride also requires caution.
• Kidney - Not recommended in severe renal impairment (eGFR <30 mL/min/1.73m²).
• Lung - Use with caution in patients with severe respiratory conditions due to the potential for lactic acidosis.

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