EMBETA TM 25 10

About

Metoprolol is a selective beta-1 adrenergic receptor blocker primarily used in the management of cardiovascular conditions. It works by blocking the action of certain natural chemicals in the body, like epinephrine, on the heart and blood vessels. This action leads to a reduction in heart rate, blood pressure, and the heart's workload, thereby improving cardiac efficiency. It is particularly effective in reducing myocardial oxygen demand, which is beneficial in conditions like angina pectoris.

The sustained-release formulation ensures a prolonged therapeutic effect, allowing for once-daily dosing and maintaining stable plasma concentrations. Its cardioselective nature at lower doses means it primarily affects the heart, potentially causing fewer respiratory side effects compared to non-selective beta-blockers. However, this selectivity can diminish at higher doses, and caution is still advised in patients with severe respiratory conditions.

Uses

• Management of hypertension (high blood pressure).
• Treatment of angina pectoris (chest pain).
• Prevention of migraine headaches.
• Management of certain cardiac arrhythmias.

Directions For Use

Take orally as directed by your physician, usually once daily with or immediately after a meal. Do not crush or chew the tablet.

Benefits

• Effectively lowers blood pressure.
• Reduces frequency and severity of angina attacks.
• Helps prevent migraine headaches.
• Improves survival post-myocardial infarction.
• Controls rapid heart rates in certain arrhythmias.
• Reduces the heart's workload.

Side Effects

• Fatigue or dizziness
• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)
• Nausea or stomach upset
• Diarrhea or constipation
• Cold hands and feet
• Shortness of breath
• Insomnia or vivid dreams
• Depression
• Rash or itching
• Sexual dysfunction
• Masking of hypoglycemia symptoms

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase dizziness.
• Pregnancy - Use only if clearly needed and the potential benefit outweighs the risk to the fetus; consult a doctor.
• Breastfeeding - Metoprolol passes into breast milk; monitor the infant for signs of beta-blockade like bradycardia.
• Liver - Use with caution in patients with severe liver impairment as metabolism may be reduced, requiring dose adjustment.
• Kidney - Generally safe in kidney disease, but dose adjustment may be needed in severe renal impairment.
• Lung - Use with caution in patients with asthma or severe COPD due to potential for bronchospasm, especially at higher doses.

Disclaimer

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