About
Entaliv 0.5 mg is an antiviral medication, specifically a nucleoside analogue, primarily used for the treatment of chronic Hepatitis B virus (HBV) infection. It works by inhibiting the HBV reverse transcriptase, an enzyme crucial for the virus's replication cycle. By blocking this enzyme, Entaliv prevents the virus from multiplying and reduces the viral load in the body. This action helps to decrease liver inflammation, prevent further liver damage, and reduce the risk of developing serious complications such as cirrhosis and hepatocellular carcinoma (liver cancer).
Entaliv is highly effective in achieving sustained viral suppression and improving liver histology in patients with chronic HBV. It is typically prescribed for long-term therapy, and consistent adherence to the daily dosage is vital for maintaining its efficacy and preventing the development of drug resistance. Regular monitoring of liver function, viral load, and renal function is essential throughout the treatment period to ensure optimal outcomes and manage any potential side effects.
Uses
- Treatment of chronic Hepatitis B virus (HBV) infection.
- Suppression of HBV DNA levels.
- Improvement of liver histology in HBV patients.
- Prevention of HBV-related liver complications.
Directions For Use
Take one tablet orally once daily on an empty stomach (at least 2 hours after and 2 hours before food), as directed by your physician.
Benefits
- Potently suppresses HBV viral replication.
- Reduces the risk of liver cirrhosis and cancer.
- Improves liver function and histology.
- Well-tolerated for long-term use.
- Helps prevent disease progression.
- Enhances overall quality of life for HBV patients.
Side Effects
- Headache
- Fatigue
- Dizziness
- Nausea
- Diarrhea
- Abdominal pain
- Insomnia
- Elevated liver enzymes
- Lactic acidosis (rare)
- Pancreatitis (rare)
- Rash
- Peripheral neuropathy (rare)
Safety Measures
- Alcohol - Avoid or significantly limit alcohol consumption as it can exacerbate liver damage, especially in patients with chronic HBV, and may worsen side effects.
- Pregnancy - Consult a doctor. Use only if the potential benefit justifies the potential risk to the fetus. Discuss with a healthcare provider for individualized advice.
- Breastfeeding - Consult a doctor. It is generally advised to avoid breastfeeding due to potential excretion into breast milk and unknown effects on the infant.
- Liver - Specifically used for liver conditions; however, monitor liver function closely, especially upon discontinuation, due to potential HBV exacerbation.
- Kidney - Dose adjustment is necessary for patients with impaired renal function; regular monitoring of kidney function is crucial.
- Lung - No specific direct lung effects, but any new or worsening respiratory symptoms should be evaluated by a healthcare professional.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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