Farmorubicin 10mg Injection

About

Farmorubicin 10mg Injection contains epirubicin, an anthracycline topoisomerase II inhibitor, which is a potent cytotoxic agent widely used in chemotherapy. Its mechanism of action involves intercalating into DNA, inhibiting topoisomerase II, and generating free radicals, all of which lead to DNA damage and ultimately programmed cell death (apoptosis) in rapidly dividing cancer cells. This broad-spectrum activity makes it effective against a variety of solid tumors and hematological malignancies. Epirubicin is particularly noted for its role in adjuvant and neoadjuvant settings for breast cancer, as well as in the treatment of lymphomas and gastric cancers.

Due to its potent nature, administration requires careful monitoring for dose-limiting toxicities, especially cardiotoxicity, which is a characteristic side effect of anthracyclines. It is typically administered intravenously under strict medical supervision as part of a comprehensive cancer treatment regimen.

Uses

• Adjuvant treatment of early breast cancer.
• Treatment of advanced breast cancer.
• Management of gastric cancer.
• Therapy for lymphomas and soft tissue sarcomas.

Directions For Use

Farmorubicin 10mg Injection is administered intravenously by a qualified healthcare professional. Dosage and administration schedule are determined by the physician based on the specific cancer type, patient's body surface area, and overall health.

Benefits

• Broad-spectrum anti-cancer activity.
• Effective against various solid tumors.
• Used in combination chemotherapy regimens.
• May improve disease-free survival.
• Established efficacy in breast cancer.
• Potent cytotoxic agent.

Side Effects

• Nausea and vomiting
• Hair loss (alopecia)
• Myelosuppression (low blood counts)
• Mucositis/stomatitis
• Cardiotoxicity (heart damage)
• Fatigue
• Diarrhea
• Red urine (harmless)
• Injection site reactions
• Skin rash
• Fever
• Amenorrhea

Safety Measures

• Alcohol - Avoid alcohol during treatment as it may exacerbate gastrointestinal side effects and potentially interact with the medication.
• Pregnancy - Contraindicated in pregnancy due to severe teratogenic effects. Women of childbearing potential must use highly effective contraception.
• Breastfeeding - Breastfeeding is strictly contraindicated during and for a period after treatment due to potential excretion into breast milk and severe harm to the infant.
• Liver - Use with extreme caution in patients with hepatic impairment; significant dose reduction is required, and liver function must be closely monitored due to increased toxicity risk.
• Kidney - Use with caution in patients with severe renal impairment; dose adjustments may be necessary, and kidney function should be regularly assessed.
• Lung - Monitor for signs of pulmonary toxicity, though rare, as anthracyclines can sometimes cause lung complications.

Disclaimer

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