FEBURIC 40MG TAB

About

Febuxostat is a potent, non-purine selective inhibitor of xanthine oxidase (XO), an enzyme crucial for the production of uric acid. By specifically blocking this enzyme, febuxostat effectively lowers serum uric acid levels, making it a cornerstone in the long-term management of chronic hyperuricemia in patients diagnosed with gout. This reduction in uric acid concentration is vital for preventing the formation of new uric acid crystals and facilitating the dissolution of existing crystals, which are responsible for painful gout flares and progressive joint damage. Febuxostat offers a valuable therapeutic option, particularly for patients who are intolerant to allopurinol or for whom allopurinol is not sufficiently effective. Its consistent use helps to stabilize uric acid levels, thereby reducing the frequency and severity of gout attacks and preserving joint integrity over time.

Uses

• Chronic management of hyperuricemia in patients with gout.
• Prevention of gout flares.
• Dissolution of uric acid crystals (tophi).
• Patients intolerant to allopurinol.

Directions For Use

Take orally once daily, with or without food, as prescribed by your doctor. Do not stop treatment during a gout flare.

Benefits

• Effectively lowers and maintains serum uric acid levels.
• Reduces the frequency and severity of gout flares.
• Helps dissolve existing uric acid crystals (tophi).
• Improves joint function and reduces pain over time.
• Offers an alternative for patients intolerant to allopurinol.
• Can be taken once daily for convenience.

Side Effects

• Liver function abnormalities
• Nausea
• Joint pain (arthralgia)
• Rash
• Gout flares (initially)
• Headache
• Diarrhea
• Dizziness
• Fatigue
• Muscle pain
• Palpitations
• Chest pain

Safety Measures

• Alcohol - Limit alcohol intake as it can increase uric acid levels and potentially worsen gout.
• Pregnancy - Not recommended during pregnancy due to insufficient data on human fetal safety.
• Breastfeeding - Not recommended during breastfeeding as it is unknown if febuxostat passes into breast milk.
• Liver - Use with caution in patients with mild to moderate hepatic impairment. Regular liver function tests are recommended.
• Kidney - Use with caution in patients with mild to moderate renal impairment. No dosage adjustment needed for mild to moderate.
• Lung - Generally safe for use in patients with lung conditions; no specific contraindications related to lung health.

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