FEMARA 2.5MG TABLET

About

Femara 2.5mg Tablet contains Letrozole, a potent and highly selective non-steroidal aromatase inhibitor. It is indicated for the adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer, extended adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy, and first-line treatment of postmenopausal women with hormone receptor-positive or unknown advanced breast cancer. Letrozole works by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogens in peripheral tissues.

By significantly reducing estrogen levels, Letrozole deprives estrogen-dependent breast cancer cells of growth stimulation, thereby inhibiting tumor growth. This mechanism is particularly effective in postmenopausal women where estrogen production primarily occurs in peripheral tissues rather than the ovaries. It is a crucial component of endocrine therapy for breast cancer, offering a well-tolerated oral treatment option.

Uses

• Adjuvant treatment of early breast cancer in postmenopausal women.
• Extended adjuvant treatment after tamoxifen therapy.
• First-line treatment for advanced breast cancer in postmenopausal women.
• Treatment of advanced breast cancer after antiestrogen therapy failure.

Directions For Use

Take orally once daily with or without food, as directed by your physician.

Benefits

• Highly effective in hormone receptor-positive breast cancer.
• Significantly reduces estrogen levels.
• Improves disease-free survival.
• Reduces risk of recurrence.
• Oral administration for convenience.
• Well-established safety and efficacy profile.

Side Effects

• Hot flashes
• Joint pain (arthralgia)
• Fatigue
• Nausea
• Headache
• Dizziness
• Bone pain
• Osteoporosis
• Hypercholesterolemia
• Peripheral edema
• Weight gain
• Hair thinning

Safety Measures

• Alcohol - No specific interaction, but excessive alcohol may worsen fatigue or liver-related side effects.
• Pregnancy - Contraindicated; can cause fetal harm. Not for use in premenopausal women.
• Breastfeeding - Not recommended; it is unknown if it passes into breast milk.
• Liver - Use with caution in severe hepatic impairment; dose adjustment may be necessary.
• Kidney - No dose adjustment required for mild to moderate renal impairment. Use with caution in severe impairment.
• Lung - No specific precautions for lung conditions.

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