About
FORMIN PG2 TAB is an oral antidiabetic medication that combines two distinct classes of glucose-lowering agents: Metformin and Pioglitazone. Metformin, a biguanide, primarily functions by reducing the amount of glucose produced by the liver and by enhancing the sensitivity of peripheral tissues, such as muscle cells, to insulin. Pioglitazone, a thiazolidinedione (TZD), works by activating peroxisome proliferator-activated receptor-gamma (PPAR-gamma) in adipose tissue, skeletal muscle, and the liver, thereby improving insulin sensitivity and reducing insulin resistance. This synergistic combination therapy is prescribed for adults with type 2 diabetes mellitus to achieve superior glycemic control when monotherapy or other combinations are insufficient, effectively targeting both glucose overproduction and insulin resistance.
Uses
- Type 2 Diabetes Mellitus
- Improvement of glycemic control
- Reduction of insulin resistance
- Lowering fasting and postprandial glucose
Directions For Use
Take orally with meals, usually once or twice daily, as prescribed by your physician. Swallow the tablet whole with water.
Benefits
- Effective blood sugar control
- Addresses insulin resistance
- Reduces hepatic glucose output
- Convenient combination therapy
- May help reduce cardiovascular risk factors (Pioglitazone)
- Helps lower HbA1c levels
Side Effects
- Hypoglycemia (less common than sulfonylureas)
- Nausea
- Diarrhea
- Abdominal pain
- Weight gain
- Fluid retention/edema
- Headache
- Upper respiratory tract infection
- Bladder cancer risk (Pioglitazone, rare)
- Bone fractures (Pioglitazone)
- Lactic acidosis (Metformin, rare but serious)
- Macular edema (Pioglitazone)
Safety Measures
- Alcohol - Avoid excessive alcohol due to increased risk of lactic acidosis and hypoglycemia.
- Pregnancy - Generally not recommended; insulin is preferred for glycemic control during pregnancy. Consult a doctor.
- Breastfeeding - Not recommended as Metformin passes into breast milk. Consult a doctor for alternatives.
- Liver - Contraindicated in active liver disease; regular monitoring of liver enzymes is essential.
- Kidney - Contraindicated in severe renal impairment (Metformin component). Dose adjustment needed for moderate impairment.
- Lung - Use with caution in conditions predisposing to heart failure, as Pioglitazone can exacerbate fluid retention.
Disclaimer
MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.
Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
| Shipping Cost |
|
| Shop Location | Assam, India |
No comments found for this product. Be the first to comment!