TRIGLIMIPREX 2 10.S

About

TRIGLIMIPREX 2 is an oral antidiabetic medication used to manage type 2 diabetes mellitus. It typically combines two or more active ingredients, such as a sulfonylurea (e.g., Glimepiride) and a biguanide (e.g., Metformin), to provide comprehensive glycemic control. Glimepiride works by stimulating the pancreas to release more insulin, while Metformin reduces glucose production by the liver and improves insulin sensitivity in peripheral tissues. This dual mechanism helps to lower blood glucose levels effectively, especially when diet and exercise alone are insufficient.

This combination therapy aims to achieve better blood sugar control, which is crucial in preventing long-term complications associated with diabetes, such as kidney disease, nerve damage, and cardiovascular issues. It is essential to use TRIGLIMIPREX 2 as part of a comprehensive diabetes management plan that includes a healthy diet, regular exercise, and consistent monitoring of blood glucose levels. Adherence to the prescribed dosage and lifestyle modifications is key to optimizing therapeutic outcomes and minimizing potential risks. Regular follow-ups with a healthcare provider are recommended.

Uses

• Management of type 2 diabetes mellitus.
• Improvement of glycemic control in adults.
• Used when diet and exercise alone are insufficient.
• As an adjunct to lifestyle modifications.

Directions For Use

Take TRIGLIMIPREX 2 with meals to reduce gastrointestinal side effects. Follow your doctor's dosage instructions carefully.

Benefits

• Provides comprehensive blood glucose control.
• Combines multiple mechanisms of action.
• Helps prevent long-term diabetic complications.
• Improves insulin sensitivity.
• Reduces hepatic glucose production.
• Convenient single-tablet regimen for multiple agents.

Side Effects

• Hypoglycemia (low blood sugar)
• Nausea
• Diarrhea
• Abdominal discomfort
• Headache
• Dizziness
• Metallic taste in mouth
• Weight gain (less common with Metformin)
• Skin rash
• Lactic acidosis (rare but serious)
• Vitamin B12 deficiency (with Metformin)
• Upper respiratory tract infection

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis.
• Pregnancy - Generally not recommended; insulin therapy is often preferred. Consult a doctor immediately if pregnant.
• Breastfeeding - Not recommended as components may pass into breast milk. Discuss alternatives with a healthcare provider.
• Liver - Contraindicated in severe liver impairment due to increased risk of lactic acidosis. Use with caution in mild cases.
• Kidney - Contraindicated in severe renal impairment; dosage adjustment is crucial in moderate kidney disease.
• Lung - Use with caution in patients with severe lung disease or conditions causing hypoxia, due to lactic acidosis risk.

Disclaimer

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