About
GLUCORYL MV 1 is a fixed-dose combination oral antidiabetic medication comprising Glimepiride (a sulfonylurea), Metformin (a biguanide), and Voglibose (an alpha-glucosidase inhibitor). Glimepiride works by stimulating the pancreas to release insulin, helping to lower blood glucose. Metformin acts by reducing glucose production in the liver, decreasing glucose absorption from the intestines, and improving the body's sensitivity to insulin. Voglibose slows down the breakdown and absorption of complex carbohydrates in the gut, thereby mitigating the rise in blood sugar after meals. This comprehensive approach addresses multiple aspects of glucose dysregulation in type 2 diabetes, offering enhanced glycemic control for patients whose blood sugar is not adequately managed by dual therapy or other regimens, aiming to reduce the risk of long-term microvascular and macrovascular complications.
Uses
- Management of type 2 diabetes mellitus.
- Improvement of glycemic control.
- When diet and exercise alone are not enough.
- As an add-on therapy to other antidiabetic agents.
Directions For Use
Take orally with meals, usually once or twice daily, as directed by your physician. Swallow the tablet whole with water.
Benefits
- Comprehensive blood sugar control.
- Targets multiple pathways of glucose metabolism.
- Reduces both fasting and post-meal glucose.
- Improved insulin sensitivity.
- May lead to modest weight loss (Metformin effect).
- Convenient fixed-dose combination.
Side Effects
- Hypoglycemia (especially with Glimepiride)
- Nausea
- Diarrhea
- Abdominal pain/discomfort
- Flatulence
- Bloating
- Headache
- Dizziness
- Lactic acidosis (rare, Metformin)
- Vitamin B12 deficiency (long-term Metformin)
- Skin reactions
- Transient visual disturbances
Safety Measures
- Alcohol - Avoid excessive alcohol consumption as it can increase the risk of lactic acidosis (Metformin) and hypoglycemia (Glimepiride).
- Pregnancy - Generally not recommended during pregnancy. Consult your doctor to discuss risks and alternative treatments.
- Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk. Seek medical advice.
- Liver - Contraindicated in severe hepatic impairment due to increased risk of lactic acidosis (Metformin) and potential for Glimepiride accumulation.
- Kidney - Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²) due to Metformin accumulation and increased risk of lactic acidosis.
- Lung - Use with caution in conditions causing hypoxia, such as severe respiratory failure, as it may increase the risk of lactic acidosis.
Disclaimer
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| Shop Location | Assam, India |
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