Jaknat 5mg Tablet

Introduction to Jaknat 5mg Tablet

Jaknat 5mg Tablet contains Tofacitinib, a disease-modifying anti-rheumatic drug (DMARD) classified under immunomodulators. It is used on its own or in combination with other medicines to treat rheumatoid arthritis, a condition where the immune system mistakenly attacks the joints, leading to pain, swelling, and reduced mobility. It is also prescribed for psoriatic arthritis, which affects both the joints and skin, and for adults with moderately to severely active ulcerative colitis, a chronic inflammatory bowel disease.

Jaknat 5mg Tablet additionally helps manage ankylosing spondylitis, an inflammatory disorder that affects the spine. In children aged 2 years and above, it can be used to treat active polyarticular juvenile idiopathic arthritis, a long-term condition causing joint pain and swelling. This medicine works by lowering the activity of the immune system and controlling inflammation.

Before using this medication, inform your doctor if you have severe infections, active or past tuberculosis, liver disease, or a history of hepatitis B, as the virus may reactivate during treatment.

Do not use Jaknat 5mg Tablet if you are allergic to tofacitinib or any of its ingredients. Seek medical advice if you develop symptoms of infection such as fever, excessive sweating, chills, cough, shortness of breath, muscle pain, unexplained weight loss, sores on the skin, difficulty swallowing, diarrhea, or stomach pain. Also inform your doctor if you have kidney, heart, lung, or liver problems, high blood pressure, high cholesterol levels, a history of TB, or if you are a current or former smoker.

Uses of Jaknat 5mg Tablet

• Rheumatoid arthritis

• Psoriatic arthritis

• Ankylosing spondylitis

• Ulcerative colitis

• Polyarticular juvenile idiopathic arthritis

• Juvenile psoriatic arthritis

Therapeutic Effects

Jaknat 5mg Tablet belongs to the Janus Kinase (JAK) inhibitor class of DMARDs. Janus kinases are enzymes involved in the signaling pathways of cytokines, which regulate immune responses. By blocking these enzymes, the medicine reduces inflammatory signals and slows down the progression of autoimmune diseases.

Interaction of Jaknat 5mg Tablet with Other Drugs

Inform your healthcare provider about all prescription medicines, OTC drugs, vaccines, supplements, and herbal preparations you are taking. Some medicines may interact with tofacitinib and increase the risk of side effects or reduce treatment effectiveness.

More Information

• Store Jaknat 5mg at 20°C to 25°C (room temperature).

• Keep it out of reach of children and pets.

• If you miss a dose, take it as soon as you remember. Skip it if your next dose is approaching.

• Do not take two doses at once.

How to Take Jaknat 5mg Tablet

Your doctor will decide the dose depending on your condition, severity, and treatment goals. Swallow the tablet whole with a glass of water—do not crush, chew, or break it. It may be taken with or without food.

Safety Advice

Breastfeeding — Unsafe

Tofacitinib passes into breast milk and may affect the baby. Avoid breastfeeding during treatment.

Alcohol — Consult Your Doctor

The effects of alcohol with this medicine are unclear. Ask your doctor before consuming alcohol.

Liver — Unsafe in Severe Disease

Not recommended in patients with severe liver impairment. Dose modifications may be required.

Lungs — Consult Your Doctor

Safety in patients with lung disorders is not clearly established. Seek guidance if you have respiratory problems.

Driving — Consult Your Doctor

Jaknat 5mg has little or no impact on driving ability, but consult your doctor if you experience symptoms that affect concentration.

Pregnancy — Unsafe

This medicine can harm the developing fetus. Avoid use during pregnancy and use effective contraception during treatment and for 4 weeks after the last dose.

Side Effects of Jaknat 5mg Tablet

Common Side Effects

• Increased cholesterol

• Headache

• Painful urination

• Nasal inflammation

• Cough or breathlessness

• Diarrhea

• Skin rashes

Serious Side Effects

• Lung cancer

• Lymphoma or white blood cell cancer

• Heart attack

• Fever, chills

• Bloody stools

• Severe abdominal pain

• Skin blistering

Word of Advice

Jaknat 5mg may interfere with vaccinations—inform your doctor about your immunization history. This medicine may affect fertility, so discuss concerns with your physician. Routine blood tests will be performed to monitor your response and ensure safety. Avoid breastfeeding while on this medicine and for at least 36 hours after the last dose. The medication may increase your risk of infections, bleeding, or bruising, so take necessary precautions and report any unusual symptoms immediately.

Disclaimer

Medehub aims to provide information that is accurate, reliable, and reviewed by healthcare experts. The content is intended solely for educational purposes and should not replace professional medical advice, diagnosis, or treatment. Always consult your doctor regarding any medical concerns or medication-related queries. Do not delay or ignore medical advice because of information you read on Medehub. Our goal is to support—not substitute—the relationship between patients and healthcare professionals.