About
Jastinib 5mg Tablet is a cutting-edge targeted therapy classified as a Janus kinase (JAK) inhibitor, designed to treat various autoimmune and inflammatory conditions. This medication operates by selectively inhibiting specific JAK enzymes, which are integral components of intracellular signaling pathways. These pathways are crucial for the transmission of signals from cytokines and growth factors, which in turn regulate immune responses and inflammatory processes. By blocking these specific enzymes, Jastinib effectively dampens the overactive immune system and reduces inflammation, thereby alleviating symptoms and slowing the progression of chronic autoimmune diseases.
As an oral medication, Jastinib offers a convenient treatment option, typically employed when conventional therapies have proven insufficient, poorly tolerated, or contraindicated. It represents a significant advancement in managing conditions such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and atopic dermatitis. Its precise mechanism of action allows for a more targeted approach to disease modification, aiming to improve patient quality of life by controlling disease activity and preventing long-term tissue damage associated with chronic inflammation.
Uses
- Rheumatoid arthritis (moderate to severe)
- Psoriatic arthritis
- Ulcerative colitis
- Atopic dermatitis
Directions For Use
Take one tablet orally once or twice daily, with or without food, as prescribed by your specialist physician.
Benefits
- Provides significant relief from inflammatory symptoms.
- Slows the progression of joint damage in arthritis.
- Improves quality of life for patients with chronic autoimmune diseases.
- Offers an effective oral treatment option.
- Can reduce the need for corticosteroids.
- Targets specific inflammatory pathways for precise action.
Side Effects
- Upper respiratory tract infections
- Headache
- Nausea
- Diarrhea
- Increased risk of serious infections (e.g., herpes zoster)
- Elevated cholesterol levels
- Elevated liver enzymes
- Anemia
- Neutropenia
- Thrombocytopenia
- Deep vein thrombosis (DVT) / Pulmonary embolism (PE)
- Gastrointestinal perforation (rare)
Safety Measures
- Alcohol - Moderate alcohol consumption is generally acceptable, but excessive intake may increase the risk of liver enzyme elevation.
- Pregnancy - Not recommended during pregnancy due to potential fetal harm. Use effective contraception during and for a period after treatment.
- Breastfeeding - Not recommended during breastfeeding as it is unknown if it passes into breast milk and could harm the infant.
- Liver - Use with caution in patients with liver impairment; regular monitoring of liver function tests is essential.
- Kidney - Dose adjustment may be necessary for patients with moderate to severe renal impairment.
- Lung - Monitor for new or worsening respiratory symptoms, as there is an increased risk of serious infections, including opportunistic infections, which can affect the lungs.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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