About

This medication belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs), which are widely utilized for their analgesic, anti-inflammatory, and antipyretic effects. NSAIDs primarily function by inhibiting the cyclooxygenase (COX) enzymes, which are pivotal in the biosynthesis of prostaglandins. Prostaglandins are key mediators of pain, inflammation, and fever within the body. By reducing the production of these inflammatory mediators, NSAIDs effectively alleviate symptoms associated with various painful and inflammatory conditions.

The therapeutic action of this drug involves both COX-1 and COX-2 inhibition, contributing to its broad spectrum of effects. It is commonly prescribed for the short-term management of acute pain, as well as for the symptomatic relief of chronic inflammatory disorders. The drug is absorbed orally, undergoes hepatic metabolism, and is primarily excreted via the kidneys. Patients should be carefully assessed for pre-existing gastrointestinal, cardiovascular, and renal conditions due to potential systemic adverse effects.

Uses

Relief of mild to moderate pain
Reduction of inflammation in musculoskeletal disorders
Management of fever
Symptomatic relief of menstrual pain

Directions For Use

Take with food or milk to minimize gastrointestinal upset. Do not exceed the prescribed dose.

Benefits

Effective pain relief
Reduces inflammation
Lowers fever
Improves mobility in inflammatory conditions
Available in convenient oral form
Fast onset of action for acute symptoms

Side Effects

Stomach upset
Nausea
Heartburn
Diarrhea
Constipation
Dizziness
Headache
Fluid retention
Increased blood pressure
Skin rash
Tinnitus
Rarely, gastrointestinal bleeding

Safety Measures

Alcohol - Concurrent use of alcohol with NSAIDs can significantly increase the risk of gastrointestinal irritation and bleeding. It is strongly advised to limit or avoid alcohol consumption.
Pregnancy - NSAIDs are generally contraindicated in the third trimester of pregnancy due to risks of premature closure of the fetal ductus arteriosus and renal dysfunction. Use in earlier trimesters should be strictly under medical guidance.
Breastfeeding - Small amounts of NSAIDs may pass into breast milk. While generally considered low risk for short-term use, consult a healthcare professional to weigh benefits against potential risks to the infant.
Liver - Use with caution in patients with pre-existing liver impairment, as NSAIDs are metabolized in the liver and can, in rare instances, cause liver enzyme elevations or injury. Regular monitoring of liver function is recommended.
Kidney - NSAIDs can impair renal function, particularly in individuals with pre-existing kidney disease, dehydration, or heart failure. Avoid or use with extreme caution, and closely monitor kidney function.
Lung - Patients with asthma, especially those with aspirin-sensitive asthma, may experience exacerbation of bronchospasm or other respiratory symptoms with NSAID use. Exercise caution and monitor respiratory status.

Disclaimer

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