About
This medication belongs to a class of drugs known as HMG-CoA reductase inhibitors, commonly referred to as statins. It works by inhibiting the enzyme HMG-CoA reductase, which is crucial for cholesterol synthesis in the liver. By reducing the production of cholesterol, it significantly lowers levels of low-density lipoprotein cholesterol (LDL-C), often called "bad" cholesterol, and total cholesterol. It also helps to lower triglycerides and can modestly increase high-density lipoprotein cholesterol (HDL-C), or "good" cholesterol.
The primary goal of this therapy is to improve the lipid profile, thereby reducing the risk of atherosclerotic cardiovascular disease, including heart attacks and strokes. It is an essential component of long-term management for individuals with hypercholesterolemia or those at high risk for cardiovascular events.
Uses
- Treatment of primary hypercholesterolemia
- Management of mixed dyslipidemia
- Primary prevention of cardiovascular disease
- Secondary prevention of cardiovascular events
Directions For Use
Take one tablet orally once daily, preferably in the evening, as directed by your physician.
Benefits
- Significantly lowers LDL ("bad") cholesterol
- Reduces the risk of heart attack
- Decreases the risk of stroke
- Improves overall lipid profile
- Slows the progression of atherosclerosis
- Generally well-tolerated for long-term use
Side Effects
- Muscle pain (myalgia)
- Headache
- Nausea
- Diarrhea
- Constipation
- Abdominal pain
- Elevated liver enzymes
- Rhabdomyolysis (rare, severe muscle breakdown)
- Fatigue
- Insomnia
- Joint pain
- Rash
Safety Measures
- Alcohol - Limit alcohol intake, as excessive consumption can increase the risk of liver problems, a potential side effect of statins.
- Pregnancy - Contraindicated during pregnancy (Category X) due to potential harm to the fetus. Do not use if pregnant or planning pregnancy.
- Breastfeeding - Contraindicated during breastfeeding as it may pass into breast milk and harm the infant.
- Liver - Contraindicated in patients with active liver disease or unexplained persistent elevations in liver transaminases. Monitor liver function tests regularly.
- Kidney - Use with caution in patients with severe renal impairment; dose adjustment may be necessary.
- Lung - No specific contraindications or precautions related to lung conditions are generally noted.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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