LORANZA 1MG

About

Lorazepam, the active ingredient in LORANZA 1MG, is a benzodiazepine medication primarily used for its anxiolytic, sedative, hypnotic, and anticonvulsant properties. It works by enhancing the effect of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain, at the GABA-A receptor. This potentiation of GABA's inhibitory action leads to a reduction in neuronal excitability, resulting in its calming and sedative effects. Lorazepam has a relatively intermediate onset and duration of action compared to other benzodiazepines, making it suitable for acute management of anxiety, insomnia, and certain seizure disorders. Its efficacy in rapidly reducing anxiety and promoting relaxation makes it a valuable short-term treatment option, though its potential for dependence necessitates careful prescribing.

Uses

• Management of anxiety disorders.
• Short-term relief of insomnia.
• Treatment of status epilepticus.
• Premedication for anesthesia.

Directions For Use

Take this medication orally, exactly as prescribed by your doctor. It can be taken with or without food. Do not stop abruptly without medical advice.

Benefits

• Rapid relief of acute anxiety.
• Effective in treating insomnia.
• Potent anticonvulsant properties.
• Useful as a pre-anesthetic agent.
• Reduces muscle spasms.
• Helps manage alcohol withdrawal symptoms.

Side Effects

• Drowsiness
• Dizziness
• Weakness
• Unsteadiness
• Blurred vision
• Headache
• Nausea
• Constipation
• Memory problems
• Confusion
• Slurred speech
• Paradoxical excitement

Safety Measures

• Alcohol - Strictly avoid alcohol as it significantly increases CNS depression, leading to severe drowsiness, respiratory depression, and potentially coma.
• Pregnancy - Not recommended, especially during the first trimester, due to potential risk of congenital malformations. Use only if clearly needed and benefits outweigh risks.
• Breastfeeding - Not recommended as lorazepam passes into breast milk and can cause sedation and feeding difficulties in the infant.
• Liver - Use with extreme caution in patients with severe hepatic impairment; dose reduction is often necessary. Monitor for increased sedation.
• Kidney - Use with caution in patients with renal impairment; dose adjustments may be required. Monitor for prolonged effects.
• Lung - Use with caution in patients with severe respiratory insufficiency (e.g., COPD, sleep apnea) due to risk of respiratory depression.

Disclaimer

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