NOXIB 120MG

About

Etoricoxib is a highly selective cyclooxygenase-2 (COX-2) inhibitor, a type of non-steroidal anti-inflammatory drug (NSAID). Its mechanism of action involves selectively blocking the COX-2 enzyme, which is primarily responsible for the synthesis of prostaglandins at sites of inflammation and pain. Unlike non-selective NSAIDs that inhibit both COX-1 and COX-2, etoricoxib's selectivity for COX-2 allows it to reduce pain and inflammation with a potentially lower risk of gastrointestinal side effects, such as ulcers and bleeding, which are often associated with COX-1 inhibition.

The 120mg strength is typically reserved for the short-term treatment of acute pain conditions, such as acute gouty arthritis, post-operative dental pain, or primary dysmenorrhea, where rapid and potent analgesic and anti-inflammatory effects are required.

Uses

• Acute gouty arthritis
• Acute pain
• Post-operative dental pain
• Primary dysmenorrhea

Directions For Use

Take one tablet orally once daily, with or without food, as prescribed by your doctor. Do not exceed the recommended dose.

Benefits

• Rapid pain relief
• Strong anti-inflammatory action
• Effective for acute pain
• Potentially lower GI side effects
• Once-daily dosing
• Improves mobility in acute conditions

Side Effects

• Abdominal pain
• Indigestion
• Nausea
• Diarrhea
• Headache
• Dizziness
• Peripheral edema
• Hypertension
• Flu-like symptoms
• Elevated liver enzymes
• Palpitations
• Skin rash

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it may increase the risk of gastrointestinal irritation and bleeding when combined with NSAIDs.
• Pregnancy - Consult a doctor. Etoricoxib is generally avoided in the third trimester due to potential fetal cardiovascular effects.
• Breastfeeding - Consult a doctor. Etoricoxib is excreted in breast milk; use with caution and only if clearly necessary.
• Liver - Use with caution in patients with liver impairment; regular monitoring of liver function tests is recommended.
• Kidney - Use with caution in patients with kidney impairment as NSAIDs can reduce renal blood flow and worsen kidney function.
• Lung - Use with caution in patients with asthma, as NSAIDs can trigger bronchospasm in susceptible individuals.

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