-19%

PEG D 75/20

Salt Composition: Pregabalin (75mg) + Duloxetine (20mg)  
Manufacturer: Ipca Laboratories Ltd  
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219.70
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177.70
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42 (19%)
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H212R1B23169
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About

This combination medication contains Diclofenac 75mg and Pantoprazole 20mg, offering a dual approach to managing pain and inflammation while protecting the gastrointestinal tract. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that effectively reduces pain, inflammation, and fever by inhibiting prostaglandin synthesis. While highly effective, NSAIDs are known to cause gastrointestinal side effects, including ulcers and bleeding. Pantoprazole, a proton pump inhibitor (PPI), works by irreversibly blocking the proton pump in gastric parietal cells, thereby reducing gastric acid secretion. This protective action significantly lowers the risk of NSAID-induced gastrointestinal complications, such as gastritis, erosions, and ulcers. The combination is particularly beneficial for patients requiring long-term NSAID therapy or those at increased risk of GI adverse events.

Uses

  • Relief of pain and inflammation in chronic conditions.
  • Management of osteoarthritis and rheumatoid arthritis.
  • Prevention of NSAID-induced gastric ulcers.
  • Treatment of ankylosing spondylitis with gastric protection.

Directions For Use

Take one tablet orally, usually once daily, preferably before a meal. Swallow the tablet whole; do not crush or chew.

Benefits

  • Effective pain and inflammation relief.
  • Protects stomach from NSAID-induced damage.
  • Reduces risk of gastric ulcers and bleeding.
  • Convenient fixed-dose combination.
  • Improves patient compliance.
  • Suitable for long-term NSAID users.

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Indigestion
  • Headache
  • Dizziness
  • Rash
  • Flatulence
  • Constipation
  • Increased blood pressure (from diclofenac)
  • Liver enzyme elevation (from diclofenac)

Safety Measures

  • Alcohol - Avoid or limit alcohol consumption as it may increase the risk of gastrointestinal bleeding and liver damage with diclofenac.
  • Pregnancy - Diclofenac is generally not recommended in the third trimester; pantoprazole use should be weighed against potential risks. Consult a doctor.
  • Breastfeeding - Both components pass into breast milk; use with caution and monitor infant for adverse effects, or consider alternative medications.
  • Liver - Use with caution in patients with liver impairment; regular monitoring of liver function tests is advised for diclofenac.
  • Kidney - Use with caution in patients with kidney impairment as NSAIDs can worsen renal function; dose adjustment may be necessary.
  • Lung - Use diclofenac with caution in asthmatic patients due to risk of bronchospasm; pantoprazole is generally safe.

Disclaimer

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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.

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