PREVA AS 75 15'S

About

This combination medication typically contains a statin, such as atorvastatin, and aspirin. Atorvastatin is an HMG-CoA reductase inhibitor that effectively lowers elevated levels of total cholesterol, LDL-C, and triglycerides, while increasing HDL-C. It works by inhibiting cholesterol synthesis in the liver, thereby reducing the formation of atherosclerotic plaques. Aspirin, a non-steroidal anti-inflammatory drug (NSAID) and antiplatelet agent, works by irreversibly inhibiting cyclooxygenase (COX) enzymes, which prevents the formation of thromboxane A2, a potent platelet aggregator.

This dual therapy is prescribed for patients at high risk of cardiovascular events, providing both lipid-lowering and antiplatelet effects to reduce the incidence of heart attacks, strokes, and other thrombotic events. It is an important component of a comprehensive cardiovascular risk reduction strategy, alongside diet and exercise.

Uses

• Secondary prevention of cardiovascular events.
• Reduction of risk in patients with established atherosclerotic disease.
• Management of dyslipidemia with antiplatelet needs.
• Prevention of recurrent myocardial infarction and stroke.

Directions For Use

Take one tablet orally once daily, preferably at the same time each day, with or without food, as advised by your doctor.

Benefits

• Comprehensive cardiovascular risk reduction.
• Combined lipid-lowering and antiplatelet effects.
• Reduced incidence of heart attacks and strokes.
• Improved patient adherence with a single pill.
• Effective for high-risk patients with existing CVD.
• Helps stabilize plaques and prevent clot formation.

Side Effects

• Muscle pain or weakness (statin component).
• Headache.
• Nausea or stomach upset.
• Indigestion or heartburn.
• Increased bleeding risk (aspirin component).
• Diarrhea or constipation.
• Abdominal pain.
• Fatigue.
• Tinnitus (ringing in ears, with high aspirin doses).
• Rash or itching.
• Increased liver enzymes.
• Gastrointestinal ulcers (aspirin component).

Safety Measures

• Alcohol - Avoid or limit alcohol due to increased risk of liver damage (statin) and gastrointestinal bleeding (aspirin).
• Pregnancy - Contraindicated; statins are teratogenic, and aspirin can cause fetal harm, especially in late pregnancy.
• Breastfeeding - Contraindicated; both components can pass into breast milk and may harm the infant.
• Liver - Contraindicated in active liver disease; monitor liver function tests closely.
• Kidney - Use with caution in severe renal impairment; monitor kidney function and adjust dose if necessary.
• Lung - Use with caution in asthmatic patients due to potential for aspirin-induced bronchospasm.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.