PRICHEK M1 FORTE 10S

About

PRICHEK M1 FORTE is a combination oral antidiabetic medication containing Glimepiride (1mg) and a higher dose of Metformin, indicated for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea, stimulates the beta cells of the pancreas to release more insulin, thereby lowering blood glucose levels. Metformin, a biguanide, primarily reduces glucose production by the liver and enhances insulin sensitivity in peripheral tissues, allowing the body to use insulin more effectively.

This combination is particularly useful for patients who require more intensive glycemic control than achieved with lower doses or monotherapy. It helps to achieve target blood sugar levels, reduce HbA1c, and mitigate the risk of long-term diabetes complications by addressing both insulin secretion and insulin resistance, especially when diet and exercise alone are insufficient.

Uses

• Management of type 2 diabetes mellitus.
• To achieve intensive glycemic control.
• When diet and exercise are insufficient.
• As an add-on to other antidiabetic agents.

Directions For Use

Take orally with meals, usually once or twice daily, as prescribed by your doctor.

Benefits

• Strong reduction in blood glucose and HbA1c.
• Comprehensive control through dual mechanisms.
• Helps prevent long-term diabetes complications.
• Improves both insulin secretion and sensitivity.
• Convenient fixed-dose combination.
• Effective for patients needing higher metformin doses.

Side Effects

• Hypoglycemia (low blood sugar)
• Nausea
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Metallic taste (metformin)
• Skin rash
• Weight gain (glimepiride)
• Lactic acidosis (rare, metformin)
• Vitamin B12 deficiency (metformin)
• Allergic reactions

Safety Measures

• Alcohol - Avoid or limit alcohol due to increased risk of hypoglycemia (glimepiride) and lactic acidosis (metformin).
• Pregnancy - Not recommended during pregnancy; consult a doctor for alternatives.
• Breastfeeding - Not advised during breastfeeding; seek medical guidance.
• Liver - Contraindicated in severe liver impairment due to metformin and glimepiride metabolism.
• Kidney - Contraindicated in severe kidney impairment; dose adjustment needed for moderate impairment.
• Lung - Use with caution in severe respiratory conditions due to potential for lactic acidosis.

Disclaimer

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