Renocel 4000 IU Injection

About

Renocel 4000 IU Injection contains recombinant human erythropoietin (rHuEPO), a glycoprotein hormone that plays a critical role in erythropoiesis, the production of red blood cells. It functions by stimulating the proliferation and differentiation of erythroid progenitor cells in the bone marrow, leading to an increase in red blood cell mass and hemoglobin levels. This medication is primarily indicated for the treatment of anemia associated with chronic kidney disease (CKD) in both dialysis and non-dialysis patients, where endogenous erythropoietin production is often deficient. It is also used to manage anemia in certain cancer patients undergoing chemotherapy and to reduce the need for allogeneic blood transfusions in specific surgical settings. Regular monitoring of hemoglobin levels and blood pressure is crucial during treatment to ensure efficacy and manage potential risks.

Uses

• Treatment of anemia associated with chronic kidney disease
• Management of anemia in cancer patients receiving chemotherapy
• Reduction of allogeneic blood transfusion in surgical patients
• Treatment of anemia in HIV-infected patients on zidovudine

Directions For Use

Administer subcutaneously or intravenously, as directed by a healthcare professional. Dosage and frequency are individualized based on patient response.

Benefits

• Effectively corrects anemia and increases hemoglobin levels
• Significantly reduces the need for blood transfusions
• Improves quality of life and reduces fatigue
• Enhances energy levels and physical activity tolerance
• Decreases cardiovascular strain associated with anemia
• Provides a targeted treatment for erythropoietin deficiency

Side Effects

• Hypertension (high blood pressure)
• Headache
• Arthralgia (joint pain)
• Fever
• Nausea
• Vomiting
• Diarrhea
• Injection site pain or irritation
• Skin rash
• Thrombosis (e.g., DVT, PE)
• Stroke
• Myocardial infarction
• Pure red cell aplasia (very rare)
• Seizures

Safety Measures

• Alcohol - No direct interaction, but excessive alcohol consumption can worsen anemia or liver function.
• Pregnancy - Use only if clearly needed and potential benefits outweigh risks to the fetus. Consult your doctor.
• Breastfeeding - Use with caution; it is unknown if erythropoietin is excreted in human milk. Consult your doctor.
• Liver - Use with caution in patients with severe liver disease; monitor liver function as needed.
• Kidney - Primary indication for anemia in CKD; monitor hemoglobin levels, iron status, and blood pressure closely.
• Lung - No specific contraindications, but monitor for thrombotic events, especially in patients with pre-existing pulmonary vascular disease.

Disclaimer

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